Results 121 to 130 of about 429,003 (305)
Advanced Science, EarlyView.Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li +8 more
wiley +1 more source
Serum Hsa_circ_0023919 is a Predictive Biomarker of Chemoresistance in CRC Treatment
International Journal of General MedicineLei Zhang,1 Chuanfa Fang,1 Weiquan Zhu,1 Wu Zhong,1 Rongqiang Ye2 1Department of Gastrointestinal Hernia, Ganzhou People’s Hospital, Ganzhou, Jiangxi, 341000, People’s Republic of China; 2Department of Hepatobiliary and Pancreatic Surgery, Ganzhou People’
Zhang L, Fang C, Zhu W, Zhong W, Ye R
doaj
Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer
Advanced Science, EarlyView.The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu +13 more
wiley +1 more source
Nouvelles acquisitions du CRC-EHESS
, 2016 La liste de nouveaux documents entrés en 2015-2016 au service de documentation du CRC est disponible en ligne. Nouvelles acquisitions du CRC-EHESS La liste est classée par cote (thème), par titre et par auteur.
CRC- EHESS, CCJ-CNRS, Centre de recherches sur la Corée 한국연구센터
core
Report : enabling team collaboration with pervasive and mobile computing : cost benefit analysis methodology [PDF]
, 2006 Construction is an information intensive industry in which the accuracy and\ud timeliness of information is paramount. It observed that the main\ud communication issue in construction is to provide a method to exchange\ud data between the site operation,
core
Advanced Science, EarlyView.Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan +5 more
wiley +1 more source
CRC 2012: Atas da 12ª Conferência sobre Redes de Computadores
, 2012 Desde 1998 que a Conferência sobre Redes de Computadores tem vindo a afirmar-se como o principal fórum nacional para a apresentação e discussão de resultados de investigação de elevada qualidade.
CRC 2012, Universidade de Aveiro
core +1 more source
UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression
Advanced Science, EarlyView.UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma +14 more
wiley +1 more source
Clocks & SleepAnimal studies show that sleep regulation depends on subcortical networks, but whether the connectivity between subcortical areas contributes to human sleep variability remains unclear.
Nasrin Mortazavi +12 more
doaj +1 more source
CRC-associated and healthy microbiome-derived candidate peptide resources
This item contains predicted microbiome-derived candidate secreted peptides identified from colorectal cancer (CRC) and healthy gut metagenomic cohorts using the secretion-aware peptide screening pipeline and multi-label prediction framework developed in
shuxin zhou (24372144) +4 more
core +1 more source