Low Expression of DYRK2 (Dual Specificity Tyrosine Phosphorylation Regulated Kinase 2) Correlates with Poor Prognosis in Colorectal Cancer. [PDF]
Dual-specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2) is a member of dual-specificity kinase family, which could phosphorylate both Ser/Thr and Tyr substrates. The role of DYRK2 in human cancer remains controversial.
Chu, Zhonghua +7 more
core +6 more sources
CRC selection for decoding of CRC-polar concatenated codes [PDF]
13 pages, 1 ...
Baicheva, Tsonka, Kazakov, Peter
openaire +2 more sources
Promotion and provision of colorectal cancer screening: a comparison of colorectal cancer control program grantees and nongrantees, 2011-2012. [PDF]
IntroductionSince 2009, the Centers for Disease Control and Prevention (CDC) has awarded nearly $95 million to 29 states and tribes through the Colorectal Cancer Control Program (CRCCP) to fund 2 program components: 1) providing colorectal cancer (CRC ...
DeGroff, Amy +6 more
core +2 more sources
Australian Biosecurity CRC for Emerging Infectious Diseases (AB-CRC) [PDF]
The Australian Biosecurity Cooperative Research Centre for Emerging Infectious Disease (AB-CRC) was a successful applicant under the Federal Government?s 2002 CRC programme, and will be formally established from July 2003. The aim of the AB-CRC is to protect Australia?s health, livestock, wildlife and economic resources by developing new capabilities ...
John S Mackenzie, Lisa Adams
openaire +1 more source
Cell line derived xenograft mouse models are a suitable in vivo model for studying tumor budding in colorectal cancer [PDF]
Tumor budding (TB) is an important prognostic parameter in colorectal cancer (CRC) and associated with metastasis. However, the mechanisms of TB have not been fully elucidated and a major limitation is the absence of in vivo models.
Dawson, Heather +6 more
core +2 more sources
A learning community approach to identifying interventions in health systems to reduce colorectal cancer screening disparities. [PDF]
Although colorectal cancer (CRC) screening in the United States has been increasing, screening rates are not optimal, and there are persistent disparities in CRC screening and mortality, particularly among minority patients.
DiCarlo, Melissa +6 more
core +2 more sources
Clinical management of endoscopically resected pT1 colorectal cancer [PDF]
Background Implementation of colorectal cancer (CRC) screening programs increases endoscopic resection of polyps with early invasive CRC (pT1). Risk of lymph node metastasis often leads to additional surgery, but despite guidelines, correct management ...
Angeletti, Stefano +11 more
core +1 more source
Pharmacoproteomic characterisation of human colon and rectal cancer [PDF]
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models for proteome-guided pre-clinical drug sensitivity studies are only beginning to emerge.
Domingo, Enric +19 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Functional Effects of let-7g Expression in Colon Cancer Metastasis. [PDF]
MicroRNA regulation is crucial for gene expression and cell functions. It has been linked to tumorigenesis, development and metastasis in colorectal cancer (CRC).
Chang, Che-Mai +10 more
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