Results 71 to 80 of about 1,107,300 (284)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Determinants of healthcare utilisation and predictors of outcome in colorectal cancer patients from Northern Iran [PDF]

open access: yes, 2016
We aimed to assess healthcare utilisation (HU), its determinants, as well as its relationship with survival in colorectal cancer (CRC) patients. This study was conducted on incident CRC cases from Northern Iran.
Aryaie, M.   +8 more
core  

Setting control of completely recyclable concrete with slag and aluminate cements [PDF]

open access: yes, 2016
A completely recyclable concrete (CRC) is designed to have a chemical composition equivalent to the one of general raw materials for cement production. By doing so, this CRC can be used at the end of its service life in cement manufacturing without the ...
De Belie, Nele   +3 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Knockdown of ANP32E inhibits colorectal cancer cell growth and glycolysis by regulating the AKT/mTOR pathway

open access: yesOpen Life Sciences
Colorectal cancer (CRC) is the third most common tumor, with an increasing number of deaths worldwide each year. Tremendous advances in the diagnosis and treatment of CRC have significantly improved the outcomes for CRC patients.
Liu Jiaojiao, Liu Yanchao, Zhao Qi
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Coupling effects in proton scattering from 40Ca [PDF]

open access: yes, 2012
Recent studies showed that neutron pickup makes a substantial contribution to the proton optical model potential (OMP) for light, mostly halo, target nuclei. Here, we extend those studies to a more “normal” target nucleus: 40Ca.
Keeley, N., Mackintosh, R. S.
core   +1 more source

Regional activity within the human amygdala varies with season, mood and illuminance

open access: yesNature Communications
The brain mechanisms through which changes in season and light exposure modulate mood may involve different nuclei of the amygdala. We aimed to test this hypothesis using 7 Tesla functional magnetic resonance imaging in 29 healthy young adults.
Islay Campbell   +12 more
doaj   +1 more source

Child rights imperatives for children in alternative care

open access: yesScottish Journal of Residential Child Care, 2017
The paper identifies human rights issues related to all children in alternative care institutions, causal factors and how these need to be addressed, and the prevention of the risks of neglect and abuse. Attention is drawn to the state's responsibilities
Hiranthi Wijemanne
doaj   +1 more source

Plasma extracellular vesicles detected by Single Molecule array technology as a liquid biopsy for colorectal cancer

open access: yesJournal of Extracellular Vesicles, 2020
Circulating extracellular vesicles (EVs) were recognized as a promising source of diagnostic biomarker. However, there are limited studies published in this area, partly due to the limited number of detection platforms capable of detecting extracellular ...
Ping Wei   +7 more
doaj   +1 more source

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