Results 91 to 100 of about 1,704,829 (382)

Adaptation of an evidence-based intervention to promote colorectal cancer screening: a quasi-experimental study [PDF]

, 2014
Background To accelerate the translation of research findings into practice for underserved populations, we investigated the adaptation of an evidence-based intervention (EBI), designed to increase colorectal cancer (CRC) screening in one limited English-
Bastani, Roshan, Chun, Alan, Kuniyuki, Alan, Taylor, Vicky, Tu, Shin-Ping, Yasui, Yutaka, Yip, Mei-Po   +6 more
core   +3 more sources

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Colorectal Cancer Screening Quality Improvement: A FITKit Mailing Initiative [PDF]

, 2019
According to the American Cancer Society, colorectal cancers are diagnosed in 1 in 22 men and 1 in 24 women in their lifetime. Despite the wide range of effective CRC screening options available in the US, the Hudson Headwaters Health Network (HHHN) has ...
Kratzer, Isabella
core   +1 more source

Changes in colorectal cancer screening intention among people aged 18–49 in the United States [PDF]

, 2014
Background: To determine whether exposure to a peer-led intervention focused on colorectal cancer (CRC) screening, physical activity, and multi-vitamin intake can lead to increased intentions to be screened for CRC once age eligible among adults under ...
Emmons, Karen M, Greaney, Mary L, Puleo, Elaine, Sprunck-Harrild, Kim, Suarez, Elizabeth Gonzalez, Syngal, Sapna   +5 more
core   +3 more sources

Awareness of Colorectal Cancer and Attitudes Towards Its Screening Guidelines in Lebanon

Annals of Global Health, 2019
Background: Screening for colorectal cancer (CRC) provides an effective strategy for early detection and prevention of the disease; however, global screening rates are still low.
Mohamad Ali Tfaily, Dana Naamani, Alaa Kassir, Sara Sleiman, Mamadou Ouattara, Munir Paul Moacdieh, Miran A. Jaffa   +6 more
doaj   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

What determines individuals' preferences for colorectal cancer screening programmes? A discrete choice experiment. [PDF]

, 2010
INTRODUCTION: In many countries uptake of colorectal cancer (CRC) screening remains low. AIM: To assess how procedural characteristics of CRC screening programmes determine preferences for participation and how individuals weigh these against the ...
Bekker-Grob, E.W. (Esther) de, Dam, L. (Leonie) van, Essink-Bot, M.L.E. (Marie-Louise), Habbema, J.D.F. (Dik), Hol, L. (Lieke), Kuipers, E.J. (Ernst), Leerdam, M.E. (Monique) van, Steyerberg, E.W. (Ewout)   +7 more
core  

The Effect of CRC Risk Calculator Use on CRC Screening Intention - Experiment Result (SPSS)

, 2023
Data was collected from the Qualtrics survey platform and exported as an SPSS dataset. The following describes the main variables of interest. X.disp: treatment group, 0: control, 1: treatment M.scpt: perceived susceptibility Y.intt: intent to sign up for screening W.gender: male=0, female=1 cleanScore: objective risk score bmi_calc: BMI agg.pre.scpt:
Lee, Jungmin, Keil, Mark, Lee, Jong Seok, Baird, Aaron, Choi, Hyoung Yong   +4 more
openaire   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Barriers and Facilitators to Colorectal Cancer Screening Among Health Fair Attendees in Utah

Journal of Primary Care & Community Health
Background: Colorectal cancer (CRC) screening uptake remains suboptimal despite the importance and effectiveness of various testing options. The purpose of our study was to identify barriers and facilitators to CRC screening in a community-based sample ...
Jordan E. Johnson, Svenja Pauleck, Andrea J.H. Williamson, Maranda Pahlkotter, Federica S. Brecha, Nathaniel Ferre, Nancy Ortiz, Robin L. Marcus, Sheetal Hardikar, Jessica N. Cohan   +9 more
doaj   +1 more source