Results 161 to 170 of about 214,860 (278)

Examining the Effectiveness of Provider Incentives to Increase CRC Screening Uptake in Neighborhood Healthcare: A California Federally Qualified Health Center. [PDF]

Health Promot Pract, 2020
Barajas M, Tangka FKL, Schultz J, Tantod K, Kempster YM, Omelu N, Hoover S, Thomas M, Richmond-Reese V, Subramanian S.   +9 more
europepmc   +1 more source

Improvement of CRC Molecular Screening Test by Normalization Strategy

, 2011
Cristina Nichita, Natsuko Imaizumi, Laura Ciarloni, Sahar Hosseinian, Sylvain Monnier‐Benoit, Curzio Rüegg, Gian Dorta   +6 more
openalex   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

IDDF2018-ABS-0146 The knowledge and perceptions on colorectal cancer (CRC) screening in general population: a 10-year comparison [PDF]

, 2018
Junjie Huang, Peter Choi, Veeleah Lok, Chunlan Chen, Colette Leung, Ada Wang, Jason Huang, Martin C. S. Wong   +7 more
openalex   +1 more source

Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang, Siqi Ren, Yuhui Li, Rongxi Chen, Ling Qiu, Yongmei Tan, Suling Chen, Huiqian Wu, Lianxi Mai, Xiao Tan, Xin Liu, Peisheng Liang, Shijia Kuang, Liansheng Wang, Jingkang Liu, Jintao Li, Yanyan Li, Qiuping Xu, Yongzhi Su, Yuehai Luo, Binyan Wu, Zijing Huang, Haotian Cao, Qunxing Li, Jinsong Li, Tianjun Lan   +25 more
wiley   +1 more source

Colonoscopy screening for colorectal cancer in Egypt: a nationwide cross-sectional study

BMC Cancer
Background Current guidelines advocate for colorectal cancer (CRC) screening in adults who are at risk by using direct visualization methods such as colonoscopy.
Abdallah R. Allam, Mostafa A. Elsayed, Ibrahim Tawfiq Daghash, Ali M. Abdelaziz, Omnia M. Mostafa, Hamdy Khaled Sabra, Ahmed Monib Eldaboush, Noor Maged Badrawy Ahmed, Rawan Tarek Elweza, Enas Sherif Adwy, Abdelrahman Elbendary Hammad, Ibrahim Ali Kabbash, Ahmed Hafez Allam, Ammar Ayman Bahbah, Marwa Ibrahim Ewis, Mohamed Mohamed Shawqi, Mostafa B. Behery, Yara Mohamed El-Said, Ahmed Eid Radwan, Mahmoud T. KhallafAllah, Omar Ali Aboshady, Mohamed A. Gouda   +21 more
doaj   +1 more source

Improving colon cancer screening in community clinics: CRC Screening and Community Clinics

, 2020
Terry C. Davis, Connie L. Arnold, Alfred Rademaker, Charles L. Bennett, Stacy Cooper Bailey, Daci Platt, Cristalyn Reynolds, Dachao Liu, Edson Carias, Pat F. Bass, Michael S. Wolf   +10 more
openalex   +1 more source

Diagnostic Accuracy of Fecal Immunochemical Test (FIT) in Bleed-positive and Bleed-negative Colorectal Cancer (CRC) Among a Cohort of 5,090 Subjects who Participated in the Colorectal Neoplasia (CRN) Screening in Brazil [PDF]

, 2023
MAARET ESKELINEN, JANNICA MEKLIN, Denise Peixoto Guimarães, Tuomas Selander, Karí Syrjänen, Matti Eskelinen   +5 more
openalex   +1 more source

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

Advanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman   +13 more
wiley   +1 more source