Results 221 to 230 of about 214,860 (278)

Patient Preferences for a Blood-Based Colorectal Cancer Screening Test: Insights From a Conjoint Analysis Survey. [PDF]

Clin Transl Gastroenterol
Clark A, Lauzon M, Griffin NM, Baldo L, Spiegel BMR, Almario CV.   +5 more
europepmc   +1 more source

CRC Screening: Current Trend and Feasibility

, 2019
Md. Rashidul Islam, Md Shahadot Hossain Sheikh, Md Abu Taher, Shima Akter Khatun, Md. Ahsan Habib, Gazi Muhammad Salauddin, Tariq A. Khan, Sudersona Saha Podder, Bidyut Debnath   +8 more
openalex   +2 more sources

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

P.12.8 COLORECTAL CANCER (CRC) SCREENING IN SOUTHERN ITALY: RESULTS OF THE FIRST 1,000 COLONOSCOPIES OF A STRUCTURED PROGRAM

, 2014
G. Rotondano, Maria Lucia Garofano, C. Meucci, A. Prisco, Stefano Sansone, M.A. Bianco   +5 more
openalex   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Thermal Cyclotrimerization Bridges Polymer‐Filler Interfaces for High‐Performance CO2 Separation Membranes

Advanced Science, EarlyView.
Thermal cyclotrimerization of nitriles converts interfacial discontinuity in MAF‐stu‐1/PIM‐1 MMMs into a continuity‐enhanced junction. Triazine–Zn2+ coordination between TR‐PIM chains and MAF‐stu‐1, together with hydrogen bonding and π–π stacking, lowers interfacial tension and builds selective CO2 pathways, enabling > 10 000 barrer CO2 permeability ...
Zhihong Lin, Kaifang Wang, Ziyi Yuan, Jiali Tang, Xiaozhen Liu, Liu Chen, Lu Shao, Xuezhong He   +7 more
wiley   +1 more source

Value of Stool-Based Colorectal Cancer Screening: Integrating Real-World Adherence, Detection, and Prevention in a Cohort-Based Modeling Analysis. [PDF]

J Clin Med
Fendrick AM, Ebner DW, Dore M, Estes C, Aranda G, Dehghani M.   +5 more
europepmc   +1 more source

Role of sigmoidoscopy and fecal occult blood testing (FOBT) in screening for colorectal cancer (CRC)

, 1998
J. F. Helm, Kalindra Simpson, Robert S. Sandler   +2 more
openalex   +1 more source

Engineered Bacteria‐Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity

Advanced Science, EarlyView.
We engineered a bacterial‐vesicular dual‐delivery platform that targets LOx to colorectal tumors, enabling lactate clearance, immune microenvironment remodeling, and microbiota modulation. This microbe–metabolism synergistic strategy effectively sensitizes colorectal cancer to radiotherapy, offering a promising approach to overcome radioresistance ...
Fei Peng, Zhe Lei, Zhehao Zhang, Zhiyue Su, Chonghai Zhang, Huan Yang, Shu Liu, Mengyuan Hu, Yuhong Wang, Lingchuan Guo, Lin Hu, Kai Yang   +11 more
wiley   +1 more source

Examining the Cost-Effectiveness of Introducing Patient Navigation Services for Colorectal Cancer Screening Among a Low-Income and Uninsured Population. [PDF]

Health Serv Insights
Chen WH, Ohsfeldt R, Côté M, Shipp E, Sanchez M, Brandford A, Bolin JN.   +6 more
europepmc   +1 more source