Results 271 to 280 of about 1,704,829 (382)

Patients‐Derived Organoids Sequencing‐based FOXP4 Facilitates Radioresistance by Transcriptionally Modifying GPX4 to Regulate ferroptosis in Colorectal Cancer

Advanced Science, EarlyView.
FOXP4 regulates GPX4 transcription to suppress ferroptosis. In CRC patients, initial biopsies established PDO cultures alongside concurrent chemoradiotherapy. Post‐treatment MRI with mrTRG scoring stratified radioresistant/sensitive cohorts. Parallelly, 8Gy‐irradiated PDOs underwent viability‐based stratification.
Qianping Chen, Yuzhao Jin, Luyu Liao, Rong Shen, Xingnan Ge, Qingyu Jiang, Ying Huang, Quanquan Sun, Dong Liu, Luying Liu, Tongxin Liu, Qinghui Dai, Xiyuan Tang, Zhe Han, Xin Gao, Xinhua Lin, Wei Mao, Ji Zhu   +17 more
wiley   +1 more source

Patient and provider perspectives on implementing patient navigation for colorectal cancer screening for Black and Latine patients: a qualitative study. [PDF]

BMC Health Serv Res
AuBuchon KE, Schubel LC, Rivera JNR, Garner D, Tran J, Urdinola S, Arem H.   +6 more
europepmc   +1 more source

A predictive model based on quantitative fecal immunochemical test can stratify the risk of CRC in an organized screening program

Leonardo Frazzoni, Silvia Pecere, Cesare Hassan, Lorenzo Fuccio, Livio Enrico Del Vecchio, Carlo Fabbri, Arrigo Arrigoni, Paola Cassoni, Dario Mazzucco, Lorenzo Orione, Giulia Gibiino, Alessandro Repici, Cristiano Spada, Federico Iacopini, Carlo Senore, Giulio Antonelli   +15 more
openalex   +1 more source

Structure and Ionic Conductivity of Halide Solid Electrolytes Based on NaAlCl4 and Na2ZnCl4

Advanced Science, EarlyView.
A solid solution forms in the Na2ZnCl4‐type phase when Al³⁺ substitutes in the Zn²⁺ tetrahedral site; correspondingly, Na+ vacancies form in the Na1 site, allowing for Na hopping. The highest ionic conductivity reaches 1.5*10−5 S cm−1 at 25 °C at the edge of the miscibility gap.
Hao Guo, Michael Häfner, Helen Grüninger, Matteo Bianchini   +3 more
wiley   +1 more source

76P Immune engager compounds screening using CRC patient-derived organoids

Claudia M.A. Pinna, K. Rakhimova, Jin Zhang, Louise Tee, L. Bills, David P. Millar, Catherine Blanc, Neeraj Lal, Elsa Rottoli, H. Oisin, Maria Manuela Gaspar, Romain Lara, Sašo Čemerski, Simon J. Dovedi, Andrew D. Beggs   +14 more
openalex   +1 more source

An Audit of Screening for Loss of Mismatch Repair (MMR) Protein Expression in Colorectal Cancers (CRC) in a Tertiary Referral Centre

, 2012
Karen A. Cadoo, Sinéad Noonan, Nuala McNicholas, Michael J. Kennedy   +3 more
openalex   +1 more source

Accelerating Combinatorial Electrocatalyst Discovery with Bayesian Optimization: a Case Study in the Quaternary System Ni‐Pd‐Pt‐Ru for the Oxygen Evolution Reaction

Advanced Science, EarlyView.
Exploring vast multinary composition spaces for electrocatalyst discovery is experimentally demanding. This study demonstrates how combinatorial synthesis, high‐throughput characterization, and Bayesian optimization can be combined to accelerate materials discovery.
Felix Thelen, Rico Zehl, Ridha Zerdoumi, Jan Lukas Bürgel, Lars Banko, Wolfgang Schuhmann, Alfred Ludwig   +6 more
wiley   +1 more source

Interventions to Increase Colorectal Cancer Screening Uptake in Rural Settings: A Scoping Review. [PDF]

Prev Chronic Dis
Kava CM, Smith JL, Kobernik EK, Eberth JM, French C, Nash SH, Zahnd WE, Hall IJ.   +7 more
europepmc   +1 more source

Developments in the roll-out and performance of CRC screening in Europe

Giulia Carbotti, Danica M. van den Berg, André Lopes Carvalho, Carlo Senore, Eveline A.M. Heijnsdijk, Harry J. de Koning, Iris Lansdorp‐Vogelaar   +6 more
openalex   +1 more source

Long Non‐Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R‐AKT‐mTOR Axis and Hepatocellular Carcinoma

Advanced Science, EarlyView.
The limited understanding of IGFR pathway activation hinders its clinical application in HCC. Here, IGFRIL is identified as a novel non‐coding activator of the IGF1R, which recruits PTBP1 to destabilize IGFBP3 mRNA and activates IGF1R, and proposes IGFRIL as a novel actionable target for HCC patients.
Jing Zhang, Chengming Gao, Haibei Li, Yuying Chen, Liting Yang, Qian Jin, Lan Feng, Xia Wang, Xinyi Liu, Hongxia Chen, Rong Ye, Yuanchao Xue, Huiyun Wang, Musheng Zeng, Ming Yang, Huaiqiang Ju, Chengzhi Gao, Guangming Zhou, Qi Zhang, Qian Zhang, Geng Qin, Yuanfeng Li, Yahui Wang, Aiqing Yang, Anfeng Si, Qingfeng Song, Fuchu He, Pengbo Cao, Gangqiao Zhou   +28 more
wiley   +1 more source