Results 281 to 290 of about 1,704,829 (382)
Spatial insights into colorectal cancer risk factors and priority areas for screening in the United Kingdom based on data from the UK Biobank. [PDF]
Yang M, Narasimhan VM, Zhan FB.
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This study synthesized a personalized neoantigen vaccine (Neo‐CRCVAS) and combined it with regorafenib, termed RegoNeo. This combination therapy significantly enhanced antitumor efficacy and promoted long‐term tumor‐specific immune memory in microsatellite stable colorectal cancer liver metastasis (MSS‐CRLM) models by increasing neoantigen‐specific ...
Hengkai Chen+11 more
wiley +1 more source
Clinical profiles and health-related quality of life changes after treatment in advanced colorectal cancer patients: a nationwide study in China. [PDF]
Liu H+15 more
europepmc +1 more source
Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities
The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley +1 more source
Theory-based chatbot for promoting colorectal cancer screening in a community setting in Hong Kong: study protocol of a randomised controlled trial. [PDF]
Hu Y+10 more
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Enhancing radiosensitization, modulating the tumor immune microenvironment, and ensuring complete resection are crucial for colorectal cancer (CRC) treatment. This study presents a multifunctional NIR‐II fluorescent nanoprobe, RVLu@ICG, which enhances radiosensitization, remodels the tumor immune microenvironment, and enables precise image‐guided ...
Yongying Dang+10 more
wiley +1 more source
Differential Outcomes in Colorectal Cancer Detection: A Comparative Study of Swedish Nationwide Screening and Fast-Track Diagnostic Pathways. [PDF]
El Deen Alkhadraa I+3 more
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