Results 61 to 70 of about 214,860 (278)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Predictors of Colorectal Cancer Screening Adherence among Male Veterans [PDF]

open access: yes, 2014
poster abstractColorectal cancer (CRC) is the second leading cause of cancer mortality. However, CRC risk can be decreased through regular CRC screening and removal of precancerous polyps during endoscopic screening tests.
Christy, Shannon M.   +4 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Evidence‐based consumer choice: a case study in colorectal cancer screening

open access: yesAustralian and New Zealand Journal of Public Health, 2003
Objectives:To elicit community preferences for colorectal cancer (CRC) screening by faecal occult blood test (FOBT) using discrete choice modeling (DCM).
Glenn Salkeld   +4 more
doaj   +1 more source

Changes in colorectal cancer screening intention among people aged 18–49 in the United States [PDF]

open access: yes, 2014
Background: To determine whether exposure to a peer-led intervention focused on colorectal cancer (CRC) screening, physical activity, and multi-vitamin intake can lead to increased intentions to be screened for CRC once age eligible among adults under ...
Emmons, Karen M   +5 more
core   +3 more sources

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Awareness of Colorectal Cancer and Attitudes Towards Its Screening Guidelines in Lebanon

open access: yesAnnals of Global Health, 2019
Background: Screening for colorectal cancer (CRC) provides an effective strategy for early detection and prevention of the disease; however, global screening rates are still low.
Mohamad Ali Tfaily   +6 more
doaj   +1 more source

Impact of family history of cancer on colorectal cancer screening: a propensity score-matched analysis from the Health Information National Trends Survey (HINTS)

open access: yesJournal of the Egyptian National Cancer Institute, 2023
Background Early detection of colon cancer leads to better survival outcomes. This can be achieved through colorectal cancer (CRC) screening. People with a family history of cancer (FHC) have increased risk of developing CRC. Increasing screening in this
Maxwell Akonde   +3 more
doaj   +1 more source

Race/ethnicity, sex and insurance disparities in colorectal cancer screening among individuals with and without cardiovascular disease

open access: yesPreventive Medicine Reports, 2021
Colorectal cancer (CRC) and cardiovascular diseases (CVD) share several risk factors. We examined the relationships between CRC screening and CVD history by race/ethnicity and sex.
Swati Sakhuja   +2 more
doaj   +1 more source

African American Patients’ Intent to Screen for Colorectal Cancer: Do Cultural Factors, Health Literacy, Knowledge, Age and Gender Matter? [PDF]

open access: yes, 2016
African Americans have higher colorectal cancer (CRC) mortality rates compared with all racial/ethnic groups. Research suggests that CRC screening interventions for African Americans target cultural variables.
Brittain, Kelly   +2 more
core   +2 more sources

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