Results 81 to 90 of about 214,860 (278)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

The access to colorectal cancer screening in Thai average-risk population: a situational study

BMC Health Services Research
Background Screening of colorectal cancer (CRC) is a national policy of Thailand to support early cancer detection. However, most of the Thai average-risk population does not have access to screening.
Siriphan Phamornpon, Thitipong Tankumpuan, Ketsarin Utriyaprasit, Cherdsak Iramaneerat   +3 more
doaj   +1 more source

A Multi-Level Fit-Based Quality Improvement Initiative to Improve Colorectal Cancer Screening in a Managed Care Population. [PDF]

, 2018
IntroductionColorectal cancer (CRC) is a common but largely preventable disease with suboptimal screening rates despite national guidelines to screen individuals age 50-75.
Betlachin, Anna, Esrailian, Eric, Garner, Omai B, Grossman, Mark, Hommes, Daniel W, May, Folasade P, Skootsky, Samuel, Yu, Christine   +7 more
core  

Equity of colorectal cancer screening: which groups have inequitable participation and what can we do about it? [PDF]

, 2011
The National Bowel Cancer Screening Program (NBCSP) offers population-based screening for colorectal cancer (CRC) across Australia. The aims of this paper were to highlight the inequities in CRC screening in South Australia (SA) and the system-related ...
Javanparast, Sara, Ward, Paul Russell, Wilson, Carlene J   +2 more
core   +1 more source

Geometric Optimization and Mechanical Performance Enhancement of Auxetic Structures for High‐Impact Applications Through Fused Deposition Modeling

Advanced Engineering Materials, EarlyView.
This study explores the mechanical performance of three auxetic structures, identifying a re‐entrant‐star hybrid as the most effective for impact absorption. Finite element simulations and experiments demonstrate significant gains in energy absorption and flexural strength after geometric optimization. This study investigates the mechanical performance
Malik Hassan, Manjusri Misra, Alexander Bardelcik, Stefano Gregori, Amar K. Mohanty   +4 more
wiley   +1 more source

Barriers and Facilitators to Colorectal Cancer Screening Among Health Fair Attendees in Utah

Journal of Primary Care & Community Health
Background: Colorectal cancer (CRC) screening uptake remains suboptimal despite the importance and effectiveness of various testing options. The purpose of our study was to identify barriers and facilitators to CRC screening in a community-based sample ...
Jordan E. Johnson, Svenja Pauleck, Andrea J.H. Williamson, Maranda Pahlkotter, Federica S. Brecha, Nathaniel Ferre, Nancy Ortiz, Robin L. Marcus, Sheetal Hardikar, Jessica N. Cohan   +9 more
doaj   +1 more source

Intermolecular Interactions as Driving Force of Increasing Multiphoton Absorption in a Perylene Diimide‐Based Coordination Polymer

Advanced Functional Materials, EarlyView.
This study uncovers the unexplored role of intermolecular interactions in multiphoton absorption in coordination polymers. By analyzing [Zn2tpda(DMA)2(DMF)0.3], it shows how the electronic coupling of the chromophores and confinement in the MOF enhance two‐and three‐photon absorption.
Simon Nicolas Deger, Anna Mauri, Yang Cui, Sebastian Josef Weishäupl, Ali Deniz Özdemir, Hamad Syed, Aleksandr Ovsianikov, Wolfgang Wenzel, Alexander Pöthig, Jürgen Hauer, Mariana Kozlowska, Roland Augustinus Fischer   +11 more
wiley   +1 more source

Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study [PDF]

, 2019
BACKGROUND: For virtually every patient with colorectal cancer (CRC), hematoxylin-eosin (HE)-stained tissue slides are available. These images contain quantitative information, which is not routinely used to objectively extract prognostic biomarkers.
Brenner, H., Chang-Claude, J., Charoentong, P., Ferber, D., Gaiser, T., Halama, N., Herpel, E., Hoffmeister, M., Jansen, L., Jäger, D., Kather, J. N., Krisam, J., Luedde, T., Marx, A., Reyes-Aldasoro, C. C., Valous, N. A., Weis, C. A., Zörnig, I.   +17 more
core   +2 more sources

Flux‐Regulated Crystallization of Perovskites Using Machine Learning‐Predicted Solvent Evaporation Rates for X‐Ray Detectors

Advanced Functional Materials, EarlyView.
By integrating machine learning into flux‐regulated crystallization (FRC), accurate prediction of solvent evaporation rates in real time, improving crystallization control and reducing crystal growth variability by over threefold, is achieved. This enhances the reproducibility and quality of perovskite single crystals, leading to reproducible ...
Tatiane Pretto, Sergey Dayneko, Antoine Pavesic Junior, Nicholas Sandor, Alexander Hart, Yuki Haruta, Magdalena Bazalova‐Carter, Marcos J. L. Santos, Makhsud I. Saidaminov   +8 more
wiley   +1 more source

Exploring Gender Differences in Colon Cancer Screening Knowledge and Health Beliefs among African Americans [PDF]

, 2013
poster abstractAfrican Americans are diagnosed with and die at higher rates from colorectal cancer (CRC) than any ethnic groups in the United States. Culturally appropriate, effective interventions are urgently needed to reduce these cancer disparities ...
Olofinkua, Oluwakemi Blessing, Rawl, Susan M.   +1 more
core