Results 181 to 190 of about 943,536 (329)

RIPK1 as a potential target to augment DC efficacy in tumor immunotherapy. [PDF]

Cancer Immunol Immunother
Mao L, Ou Y, Zhang Y, Wang M, Dong G, Khanniche A, Wang H, Wu Z, Zhang H, Hu L, Kong X.   +10 more
europepmc   +1 more source

Investigating Cre-Recombinase-Mediated DNA Looping using FRET [PDF]

, 2014
Massa J. Shoura, Stephen D. Levene
openalex   +1 more source

A Non‐Mitophagy Activity of BNIP3L/NIX in Amygdala Glutamatergic Neurons is Essential for Contextual Fear Memory Formation

Advanced Science, EarlyView.
Contextual fear conditioning induces BNIP3L‐dependent mitochondrial fission in glutamatergic neurons of the BLA, independently of mitophagy. Loss of BNIP3L elevates Drp1Ser637 phosphorylation, thereby suppressing mitochondrial fission, compromising ATP production, and attenuating excitatory synaptic transmission.
Xingxian Zhang, Xinlei Mo, Xinyu Zhou, Xiaoliang Liu, Guizhi Li, Songhui Hu, Yangyang Lu, Chenze Zhu, Jinxi Feng, Zhitong Chen, Weiwei Hu, Yihui Cui, Zhong Chen, Xiangnan Zhang   +13 more
wiley   +1 more source

Single-cell characterization of bacterial optogenetic Cre recombinases. [PDF]

iScience
Huang H, Jafarbeglou F, Dunlop MJ.
europepmc   +1 more source

An AND-Gated Drug and Photoactivatable Cre-loxP System for Spatiotemporal Control in Cell-Based Therapeutics

, 2019
Molly E. Allen, Wei Zhou, Jeyan Thangaraj, Phillip Kyriakakis, Yiqian Wu, Ziliang Huang, Phuong Ho, Yijia Pan, Praopim Limsakul, Xiangdong Xu, Yingxiao Wang   +10 more
openalex   +2 more sources

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

Risk factors associated with carbapenem-resistant Enterobacterales infections in hospitalized patients: A case-control study. [PDF]

Infez Med
Zambrano-Calderero V, Vera-Álava F, Borges M.   +2 more
europepmc   +1 more source

Hypothesis on CRE Motif Alterations in the SLC6A2 Promoter as a Molecular Mechanism for Hyperadrenergic Postural Orthostatic Tachycardia Syndrome (POTS)

Stazzone, Bianca
openalex   +1 more source

Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome

Advanced Science, EarlyView.
This study reveals a pivotal epigenetic regulatory role for the histone acetyltransferase p300, demonstrating that its acetylation of histone 3 at lysine 18 and 27 (H3K18ac and H3K27ac), alongside the formation of the p300/BRD4/SP1 complex, drives AR activation and ovarian fibrosis in PCOS.
Zhengquan Zhu, Yihan Wang, Haiyun Chen, Xinye Yu, Tingyu Wang, Yajing Weng, Meihong Guo, Ying Huang, Gaojian Tao, Wangsen Cao, Yong Wang, Daojuan Wang   +11 more
wiley   +1 more source

Prevalence and risk factors for carbapenem-resistant Enterobacterales colonization in hospitalized children in a provincial hospital in Vietnam. [PDF]

Front Cell Infect Microbiol
Dinh VAT, Trang NNT, Vo ND, Bich NHT, Tran DM, Phuc PD, Duc SL, Dung DM, Goutard F, Velavan TP, Nurjadi D, Hounmanou YMG, Jörgensen B, Song LH, My TN, Loire E, Östholm Å, Nilsson LE, Phan PH, Dalsgaard A, Larsson M, I-CRECT Consortium , Olson L, Hanberger H.   +23 more
europepmc   +1 more source