Results 171 to 180 of about 997,878 (328)

The Cre/lox system: Cre-ating unintended damage [PDF]

American Journal of Physiology-Renal Physiology, 2019
openaire   +2 more sources

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

Advanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh, Payel Bhanja, Emily Schueddig, Jufri Setianegara, Yuting Lin, Kenny Guida, Shujah Rehman, Stacey Krepel, Devin Koestler, Ronald C. Chen, Katherine L. Cook, Subhrajit Saha   +11 more
wiley   +1 more source

Fecal Carriage and Epidemiology of Carbapenem-Resistant Enterobacteriaceae Among Hospitalized Patients in a University Hospital

Infection and Drug Resistance, 2019
Qingxia Liu, Leping Liu, Yanming Li, Xia Chen, Qun Yan, Wen-en Liu Department of Clinical Laboratory, Xiangya Hospital of Central South University, Changsha, Hunan, People’s Republic of ChinaCorrespondence: Qun Yan; Wen-en LiuDepartment of Clinical
Liu Q, Liu L, Li Y, Chen X, Yan Q, Liu W
doaj  

Detecting and Avoiding Problems When Using the Cre-lox System.

Trends in Genetics, 2018
Allisa J. Song, R. Palmiter
semanticscholar   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse.

Developmental Biology, 2002
S. Hayashi, A. McMahon
semanticscholar   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Association Between Carbapenem-Resistant Enterobacterales (CRE) Colonization Status at Time of Hospital Admission and the Subsequent Development of CRE Infection and Mortality in High-Risk Patients

Infection and Drug Resistance
Basem M Alraddadi,1,2 Emily LG Heaphy,3 Muhannad S Alzahrani,1 Mouad Alqadi,1 Moayad Sami Qashqari,1 Mohammed S Alhuthali,1 Mohammad Kamal Al Hroub,4 Lama Hefni,1 Abeer N Alshukairi,1,2 Yasser Aldabbagh,5 Mohammed Qutub6 1Medicine Department, King Faisal
Alraddadi BM, Heaphy ELG, Alzahrani MS, Alqadi M, Qashqari MS, Alhuthali MS, Al Hroub MK, Hefni L, Alshukairi AN, Aldabbagh Y, Qutub M   +10 more
doaj  

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

Advanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

Multicenter Clinical and Molecular Epidemiological Analysis of Bacteremia Due to Carbapenem-Resistant Enterobacteriaceae (CRE) in the CRE Epicenter of the United States

Antimicrobial Agents and Chemotherapy, 2017
M. Satlin, Liang Chen, G. Patel, A. Gomez-Simmonds, G. Weston, A. Kim, S. Seo, Marnie E. Rosenthal, S. Sperber, S. Jenkins, Camille L. Hamula, A. Uhlemann, M. Levi, B. Fries, Yi-Wei Tang, S. Juretschko, A. Rojtman, T. Hong, B. Mathema, M. Jacobs, T. Walsh, R. Bonomo, B. Kreiswirth   +22 more
semanticscholar   +1 more source