Results 191 to 200 of about 943,536 (329)

Minocycline impairs TNF-α-induced cell fusion of M13SV1-Cre cells with MDA-MB-435-pFDR1 cells by suppressing NF-κB transcriptional activity and its induction of target-gene expression of fusion-relevant factors [PDF]

, 2019
Julian Weiler, Thomas Dittmar
openalex   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

Single-Cell Analyses Reveal IKKα Regulates the Interaction Between Macrophages and T Cells in the Doxorubicin-Induced Cardiomyopathy. [PDF]

Inflammation
Chen G, Yao Y, Jiang Y, Qi H, Liu Y, Yin L, Li J, Cao Y, Chen X, Zhu Y, Liu S, Tao Z.   +11 more
europepmc   +1 more source

A glimpse of Cre-mediated controversies in epicardial signalling [PDF]

, 2013
Firulli, Anthony B., Shou, Weinian, Zhang, Wenjun   +2 more
core   +1 more source

Context‐Dependent Role of GDF15: GDF15+ Tumor‐Associated Macrophages Suppress OSCC Progression by Enhancing Phagocytosis

Advanced Science, EarlyView.
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou, Zhihang Zhou, Houyu Ju, Chaoyang Guo, Fangxing Zhu, Yiyi Zhang, Xu Chen, Tongchao Zhao, Laiping Zhong, Jingzhou Hu   +9 more
wiley   +1 more source

Endothelial C-type natriuretic peptide/guanylyl cyclase-B signaling prevents pulmonary arterial hypertension. [PDF]

Nat Commun
Yanagisawa H, Kuwahara K, Nakagawa Y, Moriuchi K, Kinoshita H, Inazumi H, Kanamori T, Nishikimi T, Oya M, Nakao K, Ueda Y, Nakamura D, Shimizu K, Yoshie K, Tanaka S, Nakajima D, Sakanoue I, Yasoda A, Nakao K, Kimura T, Ono K.   +20 more
europepmc   +1 more source

History and Future Perspective of CRES-T:A Method to Convert Transcriptional Activators to Repressors in Plants

, 2014
展隆 光田, 優 高木
openalex   +2 more sources

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Association between creatinine-to-body weight ratio and arterial stiffness: a cross-sectional and longitudinal study in the Chinese population. [PDF]

Front Cardiovasc Med
Shen Y, Zhang W, Tian X, Zhang Y, Xu Q, Xia X, Zheng C, Han X, Zhao X, Wang A.   +9 more
europepmc   +1 more source

Development of Diet-Induced Obesity (DIO) in the Dbc1^LoxP/LoxP;CRE mouse model.

Leonardo Santos (477304), Rafael Sebastián Fort (6094088), Geraldine Schlapp (10745912), Karina Cal (406123), Valentina Perez-Torrado (21238747), Maria Noel Meikle (21238750), Ana Paula Mulet (10745918), Camila Espasandín (21238753), Camila Chiesa (21238756), José R. Sotelo-Silveira (8174763), Jose M. Verdes (21238759), Paola Contreras (21238762), Aldo J. Calliari (21238765), Martina Crispo (483483), Jose L. Badano (12733760), Carlos Escande (372234)   +15 more
openalex   +1 more source