Results 1 to 10 of about 98,107 (317)

TAT-CRE inhalation enables tumor induction corresponding to adenoviral Cre-recombinase in a lung cancer mouse model [PDF]

Communications Biology
Cre-recombinase inducible model systems are extensively used in cancer research to manipulate gene expression in specific tissues and induce autochthonous tumor growth.
Tabea Gewalt, Anna M. Dmitrieva, Felix Elsner, Xinlei Zhao, Daniel Dimitri Sieber, Ilayda Gülsen Kocak, Qian Yang, Claudia Viktoria Orschel, Naja Maria Eckert, Bianca Goebel, Marieke Nill, Franziska Peter, Arndt Hartmann, Filippo Beleggia, Margarete Odenthal, Hans Christian Reinhardt, Roland Tillmann Ullrich, Frederik Graw, Lydia Meder   +18 more
doaj   +4 more sources

A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing [PDF]

Nature Communications, 2022
Achieving spatial control of gene expression is important. Here the authors report an optimised photoactivatable Cre recombinase system, doxycycline- and light-inducible Cre recombinase (DiLiCre), and generate a DiLiCre mouse line which they use for ...
Miguel Vizoso, Colin E. J. Pritchard, Lorenzo Bombardelli, Bram van den Broek, Paul Krimpenfort, Roderick L. Beijersbergen, Kees Jalink, Jacco van Rheenen   +7 more
doaj   +2 more sources

Expression of Cre recombinase in dopaminoceptive neurons [PDF]

BMC Neuroscience, 2007
Background Dopamine-activated signaling regulates locomotor and emotional responses and alterations in dopamine-signaling are responsible of several psychomotor disorders. In order to identify specific functions of these pathways, the Cre/loxP system has
Casanova Emilio, Westphal Magdalena, Dassesse Donald, Parlato Rosanna, Lemberger Thomas, Turiault Marc, Tronche François, Schiffmann Serge N, Schütz Günther   +8 more
doaj   +5 more sources

Diverse Cre recombinase expression pattern in Albumin-Cre driver rats. [PDF]

Exp Anim
Rats (Rattus norvegicus) have been widely utilized as model animals due to their physiological characteristics, making them suitable for surgical and long-term studies. They have played a crucial role in biomedical research, complementing studies conducted in mice.
Ishida S, Taguchi K, Iida R, Hattori K, Taketsuru H, Yoshimi K, Yamamoto M, Mashimo T.   +7 more
europepmc   +2 more sources

Cerebellar granule cell Cre recombinase expression [PDF]

genesis, 2003
AbstractSummary: The cerebellum maintains balance and orientation, refines motor action, stores motor memories, and contributes to the timing aspects of cognition. We generated two mouse lines for making Cre recombinase‐mediated gene disruptions largely confined to adult cerebellar granule cells.
M. Isabel Aller, Alison Jones, Daniela Merlo, Marta Paterlini, Axel H. Meyer, U. Amtmann, Stephen G. Brickley, Helen E. Jolin, Andrew N. J. McKenzie, Hannah Monyer, Mark Farrant, William Wisden   +11 more
openalex   +3 more sources

Optogenetic control of early embryos labeling using photoactivatable Cre recombinase 3.0 [PDF]

FEBS Open Bio
Establishing a highly efficient photoactivatable Cre recombinase PA‐Cre3.0 can allow spatiotemporal control of Cre recombinase activity. This technique may help to elucidate cell lineages, as well as facilitate gene and cell function analysis during ...
Kumi Morikawa, Akira Nagasaki, Lue Sun, Eihachiro Kawase, Tatsuhiko Ebihara, Yasuaki Shirayoshi   +5 more
doaj   +2 more sources

Hidden Caveat of Inducible Cre Recombinase [PDF]

Immunity, 2019
Makoto Kurachi, Shin Foong Ngiow, Junko Kurachi, Zeyu Chen, E. John Wherry   +4 more
openalex   +3 more sources

Cardiac-Specific Expression of Cre Recombinase Leads to Age-Related Cardiac Dysfunction Associated with Tumor-like Growth of Atrial Cardiomyocyte and Ventricular Fibrosis and Ferroptosis. [PDF]

Int J Mol Sci, 2023
Li Z, Duan Q, Cui Y, Jones OD, Shao D, Zhang J, Gao Y, Cao X, Wang S, Li J, Lei X, Zhang W, Wang L, Zhou X, Xu M, Liu Y, Ma J, Xu X.   +17 more
europepmc   +3 more sources

Robust Cre recombinase activity in the biotrophic smut fungus Ustilago maydis enables efficient conditional null mutants in planta. [PDF]

Genetics, 2022
de la Torre A, Jurca M, Hoffmann K, Schmitz L, Heimel K, Kämper J, Pérez-Martín J.   +6 more
europepmc   +3 more sources

A method for TAT-Cre recombinase-mediated floxed allele modification in ex vivo tissue slices. [PDF]

Dis Model Mech, 2023
Cheong SS, Luis TC, Stewart M, Hillier R, Hind M, Dean CH.   +5 more
europepmc   +2 more sources