Results 191 to 200 of about 98,107 (317)
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil +11 more
wiley +1 more source
Theme I: angiotensin activation mechanisms in hypertension Genetic manipulation of the RAS using the Cre-LoxP recombinase system. [PDF]
David E. Stec
openalex +1 more source
Abstract figure legend In cortical layer (L)5 pyramidal neurons we found that mitochondria in the axon initial segment (AIS) are distributed non‐uniformly and display robust calcium (Ca2+) uptake during action potential (AP) firing. Because the AIS is the site for the initiation of APs, which are shaped by cytosolic Ca2+ levels, we hypothesized that ...
Koen Kole, Maarten H.P. Kole
wiley +1 more source
Myh6 promoter-driven Cre recombinase excises floxed DNA fragments in a subset of male germline cells. [PDF]
Sheldon C +8 more
europepmc +1 more source
Generation of a transgenic mouse model with chondrocyte‐specific and tamoxifen‐inducible expression of Cre recombinase [PDF]
Mo Chen +6 more
openalex +1 more source
Exploring Affordable Curative Therapy for Sickle Cell Disease in Africa: A Comprehensive Overview
ABSTRACT The practical aspects of developing curative treatments for sickle cell disease (SCD) in Africa, such as gene therapy and hematopoietic stem cell transplantation, involve strengthening healthcare infrastructure, training healthcare professionals, establishing regional treatment centers, and creating national SCD programs.
Adetola A. Kassim +2 more
wiley +1 more source
Inserting Cre recombinase into the Prolactin 8a2 gene for decidua-specific recombination in mice. [PDF]
Dickson MJ +8 more
europepmc +1 more source
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan +9 more
wiley +1 more source
In Vivo Intra-Uterine Delivery of TAT-Fused Cre Recombinase and CRISPR/Cas9 Editing System in Mice Unveil Histopathology of Pten/p53-Deficient Endometrial Cancers. [PDF]
Navaridas R +11 more
europepmc +1 more source

