Results 211 to 220 of about 98,107 (317)

ZNF384‐Driven Fibulin‐1 Exacerbates Vascular Stiffness via TGF‐β/Smad3‐Mediated Senescence and Fibrosis

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
This article elucidates the regulatory molecular mechanisms of Fibulin‐1 (Fbln1) in vascular stiffness and explores potential therapeutic interventions. Zinc Finger Protein 384 (ZNF384) binds to the Fbln1 promoter, driving its expression. Fbln1 activates the TGF‐β/Smad3 axis, promoting vascular smooth muscle cell (VSMC) senescence and collagen ...
Dan Yan   +11 more
wiley   +1 more source

Nanobody-based RFP-dependent Cre recombinase for selective anterograde tracing in RFP-expressing transgenic animals. [PDF]

open access: yesCommun Biol, 2022
Inutsuka A   +7 more
europepmc   +1 more source

DNA binding induces a cis -to- trans switch in Cre recombinase to enable intasome assembly

open access: green, 2020
Aparna Unnikrishnan   +5 more
openalex   +2 more sources

Ketone Body Supplementation Exerts Renoprotective Effects Against Adenine‐Induced Kidney Injury via OXCT1‐Mediated Ketolysis in Mice

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
1,3‐Butanediol is a ketone body precursor that is directly converted into the ketone bodies, β‐hydroxybutyrate (BHB), in the liver. When renal ketolysis, regulated by 3‐oxoacid CoA‐transferase 1 (OXCT1), is preserved, BHB supplementation exerts renoprotective effects.
Shoji Omachi   +13 more
wiley   +1 more source

Characterization of a rat model expressing Cre recombinase in oxytocinergic neurons: NTac:SD-Oxt<sup>em1(cre)Sage</sup>. [PDF]

open access: yesNeuroscience
Martin TJ   +11 more
europepmc   +1 more source

Cre recombinase microinjection for single-cell tracing and localised gene targeting.

open access: yesDevelopment, 2023
Sendra M   +6 more
europepmc   +1 more source

Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia. [PDF]

open access: yesLeukemia, 2023
Straube J   +15 more
europepmc   +1 more source

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