This article elucidates the regulatory molecular mechanisms of Fibulin‐1 (Fbln1) in vascular stiffness and explores potential therapeutic interventions. Zinc Finger Protein 384 (ZNF384) binds to the Fbln1 promoter, driving its expression. Fbln1 activates the TGF‐β/Smad3 axis, promoting vascular smooth muscle cell (VSMC) senescence and collagen ...
Dan Yan +11 more
wiley +1 more source
Protocol for establishing primary murine colonic fibroblast culture with induction of loxP/loxP deletion using transducible TAT-Cre recombinase. [PDF]
McAninch C +4 more
europepmc +1 more source
Nanobody-based RFP-dependent Cre recombinase for selective anterograde tracing in RFP-expressing transgenic animals. [PDF]
Inutsuka A +7 more
europepmc +1 more source
Iterative pathway engineering of the diatom Phaeodactylum tricornutum to enhance the biosynthesis of long‐chain polyunsaturated fatty acids using the Cre recombinase‐mediated marker recycling [PDF]
Junkai Zhu +7 more
openalex +1 more source
DNA binding induces a cis -to- trans switch in Cre recombinase to enable intasome assembly
Aparna Unnikrishnan +5 more
openalex +2 more sources
1,3‐Butanediol is a ketone body precursor that is directly converted into the ketone bodies, β‐hydroxybutyrate (BHB), in the liver. When renal ketolysis, regulated by 3‐oxoacid CoA‐transferase 1 (OXCT1), is preserved, BHB supplementation exerts renoprotective effects.
Shoji Omachi +13 more
wiley +1 more source
Characterization of a rat model expressing Cre recombinase in oxytocinergic neurons: NTac:SD-Oxt<sup>em1(cre)Sage</sup>. [PDF]
Martin TJ +11 more
europepmc +1 more source
Cre recombinase microinjection for single-cell tracing and localised gene targeting.
Sendra M +6 more
europepmc +1 more source
Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia. [PDF]
Straube J +15 more
europepmc +1 more source

