Results 231 to 240 of about 98,107 (317)

Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.

, 1995
Koji Araki, Masatake G. Araki, Jun‐ichi Miyazaki, P Vassalli   +3 more
openalex   +2 more sources

Efficient Sequential Gene Regulation via FLP‐ and Cre‐Recombinase Using Adenovirus Vector in Mammalian Cells Including Mouse ES Cells [PDF]

, 2006
Saki Kondo, Yuzuka Takahashi, Seiji Shiozawa, Hirotake Ichise, Nobuaki Yoshida, Yumi Kanegae, Izumu Saito   +6 more
openalex   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang, Heng Yang, Xinjie Gao, Zengyu Zhang, Ruiyuan Weng, Yuchao Fei, Jiabin Su, Hanqiang Jiang, Wei Ni, Yuxiang Gu   +9 more
wiley   +1 more source

Systematic optimization and prediction of cre recombinase for precise genome editing in mice. [PDF]

Genome Biol
Erhardt V, Hartig E, Lorenzo K, Megathlin HR, Tarchini B, Hosur V.   +5 more
europepmc   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

A rapid and efficient red-light-activated Cre recombinase system for genome engineering in mammalian cells and transgenic mice. [PDF]

Nucleic Acids Res
Zhou Y, Wei Y, Yin J, Kong D, Li W, Wang X, Yao Y, Huang Q, Li L, Liu M, Qiao L, Li H, Zhao J, Zhong TP, Li D, Duan L, Guan N, Ye H.   +17 more
europepmc   +1 more source

Adeno-associated virus (AAV)-mediated Cre recombinase expression in melanopsin ganglion cells without leaky expression in rod/cone photoreceptors. [PDF]

J Neurosci Methods, 2023
Reifler AN, Wong KY.
europepmc   +1 more source

Efficient deletion of LoxP-flanked selectable marker genes from the genome of transgenic pigs by an engineered Cre recombinase

, 2020
Xiaoling Huang, Xian Zou, Zhiqian Xu, Fei Tang, Junsong Shi, Enqin Zheng, Dewu Liu, Stefan Moisyadi, Johann Urschitz, Zhenfang Wu, Zicong Li   +10 more
openalex   +2 more sources

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, Volume 13, Issue 16, 18 March 2026.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source