Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei. [PDF]
Das S +10 more
europepmc +1 more source
Generation of scalable cancer models by combining AAV-intron-trap, CRISPR/Cas9, and inducible Cre-recombinase. [PDF]
Boddu PC +5 more
europepmc +1 more source
A New System for Stringent, High-Titer Vesicular Stomatitis Virus G Protein-Pseudotyped Retrovirus Vector Induction by Introduction of Cre Recombinase into Stable Prepackaging Cell Lines [PDF]
Tohru Arai +10 more
openalex +1 more source
Sex and life experience shape locus coeruleus pretangle tau pathology
Abstract INTRODUCTION Alzheimer's disease features early a pathology in the locus coeruleus (LC), yet how sex and life experience shape LC vulnerability remains poorly understood. METHODS We expressed pseudophosphorylated human tau (htauE14) in LC neurons of TH‐Cre rats and exposed both sexes to early‐ or late‐life enrichment or stress.
Zia Hasan +10 more
wiley +1 more source
Specific, or not specific, that is the question: Is Cre recombinase deleting your favorite gene only in cardiomyocytes? [PDF]
Ronda OAHO, Roderick HL.
europepmc +1 more source
CDC42‐Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity
CDC42‐effector proteins 1/2 are present in CNS myelin. They facilitate the higher order structure of myelin septin filaments. Their loss impairs septin‐dependent scaffolding of myelin. Myelin outfoldings do not cause secondary neuropathology per se. ABSTRACT The regular structure of CNS myelin requires specialized structural proteins, including septin ...
Sophie Hümmert +14 more
wiley +1 more source
A noninvasive photoactivatable split-Cre recombinase system for genome engineering in zebrafish. [PDF]
Elsaid R +4 more
europepmc +1 more source
Cre Recombinase Driver Mice Reveal Lineage-Dependent and -Independent Expression of Brs3 in the Mouse Brain. [PDF]
Mogul AS +8 more
europepmc +1 more source
Characterization of Cre recombinase models for the study of adipose tissue [PDF]
Elise Jeffery +7 more
openalex +1 more source
Lactate Dehydrogenase Inhibition Reverts the Fatty Acid‐Induced Neurotoxic Phenotype of Astrocytes
ALS models display increased LD accumulation. LD accumulation is linked to a neurotoxic phenotype in astrocytes. Lactate dehydrogenase inhibition reverts LD accumulation in ALS astrocytes. ABSTRACT Astrocytes are central to lipid metabolism in the central nervous system.
Daniel Esteve +5 more
wiley +1 more source

