Results 281 to 290 of about 98,107 (317)
The X Factor in Immunity: Sex Differences Shaped by the X Chromosome
ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic +2 more
wiley +1 more source
Cre‐driver mouse lines are widely used for targeted gene manipulation, yet their baseline phenotypes are often assumed to be neutral. Here, we reveal hidden behavioral and synaptic alterations in the commonly used NEX‐Cre line, including changes in locomotion, anxiety‐like behavior, reward‐related behavior, and region‐specific dendritic spine density ...
Kim Renken, Olivia Andrea Masseck
wiley +1 more source
A High‐Resolution Transcriptomic Atlas of Cell Types in the Ventral Visual Thalamus
Visual information from the eyes travels from retinal ganglion cells (RGCs) to reach the brain through several relay centers. One of these centers, the ventral lateral geniculate nucleus (vLGN), is much less understood than others. In this study, we created the first detailed map of the different cell types found in the mouse vLGN.
Katelyn Stebbins +5 more
wiley +1 more source
Correction to "Stable Transgenic Mouse Strain with Enhanced Photoactivatable Cre Recombinase for Spatiotemporal Genome Manipulation". [PDF]
europepmc +1 more source
Mechanisms of Acetylcholine release, including typical and atypical release under neuronal blockade. Left panel illustrates the classical (quantal) cholinergic transmission and the right panel the mechanism described in the present study. High‐Affinity Choline Transporter (HCT), Acetylcholine (ACh), Acetylcholinesterase (ACE), and Tetrodotoxin (TTX ...
A. Martinez‐Daunis +4 more
wiley +1 more source
Transgene‐Free, Gene‐Edited Cavendish Bananas (Musa acuminata, AAA)
ABSTRACT Global consumer acceptance of gene‐edited food crops is increasing with new breeding technologies that can modify the genome without foreign DNA integration. Here, we report an Agrobacterium‐based system for transgene‐free, gene editing of the banana cultivar, Cavendish.
Maiko Kato +6 more
wiley +1 more source
SUMMARY Wheat is a staple crop critical for global food security, and its continuous genetic improvement is essential to meet the demands of a growing population. Efficient, genotype‐independent transformation is a major bottleneck in wheat functional genomics and gene editing.
Sadiye Hayta +8 more
wiley +1 more source
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Cre Recombinase and Other Tyrosine Recombinases
Chemical Reviews, 2016Tyrosine-type site-specific recombinases (T-SSRs) have opened new avenues for the predictable modification of genomes as they enable precise genome editing in heterologous hosts. These enzymes are ubiquitous in eubacteria, prevalent in archaea and temperate phages, present in certain yeast strains, but barely found in higher eukaryotes.
Gretchen, Meinke +4 more
openaire +2 more sources
Safety Assessment of Cre Recombinase
Journal of Agricultural and Food Chemistry, 2006Cre recombinase, when used as a tool in agricultural biotechnology, can precisely excise DNA sequences that may be useful in the introduction of a new trait but are not needed in the commercial product. Although the cre genetic material would not be present in the final product, the present studies were performed to assess the safety of Cre recombinase
Ronald E, Hileman +4 more
openaire +2 more sources

