Results 141 to 150 of about 41,095 (303)
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
These images were digitized from a 35 mm photographic slide. The slides represented in this collection were created for the Navajo Nights multimedia production exhibited at Flandrau Science Center & Planetarium.PAN (E): 3-Part panoramaThese images from ...
Flandrau Science Center & Planetarium, University of Arizona
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Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Ontological Ecology: The Created World in Early Christian Monastic Spirituality
This thesis analyzes the ability of early Christian monastic spirituality to contribute fruitful theological principles and spiritual practices to the contemporary Christian response to climate change.
Howland, Scott Charles
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Weaving Regenerative Value Through Nature-Inclusive Stakeholder Engagement: Insights From Indigenous Businesses in the Sierra Nevada. [PDF]
Oberholzer S.
europepmc +1 more source
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
This image was digitized from a 35 mm photographic slide. The slides represented in this collection were created for the Navajo Nights multimedia production exhibited at Flandrau Science Center & Planetarium.SL (61)This image from the Navajo Nights ...
Flandrau Science Center & Planetarium, University of Arizona
core

