Results 121 to 130 of about 2,394,808 (287)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Omniscient beings are dialetheists

open access: yes, 2007
From first paragraph: Although self-referential, there is nothing self-stultifying about the sentence S below. If no omniscient being exists, it is, quite straightforwardly, true.
Milne, Peter
core  

Alien Beings

open access: yes, 2016
Cover for Alien Beings, from the RISD Library Zine Collection.https://digitalcommons.risd.edu/specialcollections_zinecollection/1500/thumbnail ...
Ķeniņš, Laura   +2 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Artificial Intelligence: The Perfect Psychopath

open access: yesCadmus
This paper argues that any artificially intelligent system created by humans will be functionally a replica of the ideas, beliefs and values of the human beings who create it.
Peter L. Nelson
doaj  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Trash Aesthetics and the Sublime: Strategies for Visualizing the Unrepresentable within a Landscape of Refuse

open access: yes, 2015
Trash Aesthetics and the Sublime: Strategies for Visualizing the Unrepresentable within a Landscape of Refuse by Emit Snake-Beings - nanocrit.com - nanocrit.com. Representations of waste are something intangible and difficult to grasp.
Emit Snake-Beings
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Essence and Personality in Grotowski and Gurdjieff

open access: yesRevista Brasileira de Estudos da Presença, 2013
This article establishes relationships between working words and concepts in the work of Grotowski and Gurdjieff. Particularly, it investigates concepts of essence and personality, common to Grotowski and Gurdjieff, relating them to the presence and ...
Mauro Rodrigues
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

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