Results 51 to 60 of about 2,394,808 (287)

History of Epidemics and COVID-19

open access: yesBezmiâlem Science, 2020
In archaeological excavations, it has been reported that formations resembling bacterial fossils are found among the rock layers and they belong to millions of years ago.
Pelin YÜKSEL MAYDA   +1 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Amos oor die ampte en die kultus (erediens): die betekenis vir vandag

open access: yesIn die Skriflig, 2000
Amos on the offices and the cult: the meaning for us today In this article Amos’ attitude towards the offices of king, priest and prophet is explored against the background of the rest of the Old Testament.
J.L. Helberg
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Response to Melissa Raphael

open access: yesApproaching Religion, 2016
A response to Melissa Raphael’s article ‘The creation of beauty by its destruction: the idoloclastic aesthetic in modern and contemporary Jewish art’.
Ruth Illman
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

National Co-ordination of the Fight against Trafficking in Human Beings: Recommendations for Poland as a 'New' EU Member State [PDF]

open access: yes
As a world-wide problem, trafficking in human beings now attracts some well-deserved attention after years of political reservation and operational hesitation in European Union Member States.
Filip Jasinski
core  

Under the light of Quran-Hadith_Land ownership and opinion of religious leaders

open access: yesThe Islamic Culture, 2019
Al Mighty ALLAH is the true owner of this world and all material things in it. Al Mighty ALLAh has created this world for human beings and granted thme its ownership and of all material things in it.there is no contradiction in this ownership because ...
Dr. Muhammad IShaq
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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