Results 61 to 70 of about 2,394,808 (287)
Childfree women as occupational beings
, 2019 Social norms and cultural expectations have long intimated that to be a woman is to be a mother (Peterson and Engwall 2013). However times are changing with increasing numbers of women choosing to be child free (Ashburn-Nardo 2017).
Wells, G.
core
Community co-created distributed manufacturing
This project aims to develop a blueprint for a co-created, distributed, community-based manufacturing platform in the UK with a business model to support its financial viability and scalability. The research questions which we address are: • What are the
Daniel, J.
core +1 more source
ReligionsThis article aims to examine how social media has changed the way human beings perceive themselves, exerting a tyrannical influence over personal image, leading people to aesthetic procedures and surgeries.
Henrique Mata de Vasconcelos
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Role of the Soul in Humans and Other Living Beings in the Aristotelian Tradition
, 2023 The study of the relationship between the human being and other living beings receives great attention during both the Humanism and the Renaissance. The Aristotelian tradition studies the relationship between the human being and other living beings ...
Ennio De Bellis
core
INTEGRATING EVOLUTION: A CONTRIBUTION TO THE CHRISTIAN DOCTRINE OF CREATION
Zygon, 1994 . Science has demonstrated that the universe creates itself through its own history. This history is the result of a probabilistic process, not a deterministic execution of a plan.
doaj +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
TRAFFICKING IN HUMAN BEINGS [PDF]
, 2022 Trafficking in human beings, also known as slavery in modern times, is a serious crime as well as a violation of fundamental human rights and dignity. The purpose of trafficking is to exploit vulnerable persons for the sole purpose of profit. Every state
Xhemaili, Luljeta
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source