Results 271 to 280 of about 322,419 (302)
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Creatine transporters: A reappraisal
Molecular and Cellular Biochemistry, 2004Creatine (Cr) plays a key role in cellular energy metabolism and is found at high concentrations in metabolically active cells such as skeletal muscle and neurons. These, and a variety of other cells, take up Cr from the extra cellular fluid by a high affinity Na(+)/Cl(-)-dependent creatine transporter (CrT). Mutations in the crt gene, found in several
Speer, Oliver +7 more
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Creatine metabolism and the consequences of creatine depletion in muscle
Molecular and Cellular Biochemistry, 1994Currently, considerable research activities are focussing on biochemical, physiological and pathological aspects of the creatine kinase (CK)-phosphorylcreatine (PCr)-creatine (Cr) system (for reviews see [1,2]), but only little effort is directed towards a thorough investigation of Cr metabolism as a whole.
Markus Wyss, Theo Wallimann
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Nature Metabolism, 2019
Pancreatic ductal adenocarcinoma is particularly metastatic, with dismal survival rates and few treatment options. Stiff fibrotic stroma is a hallmark of pancreatic tumours, but how stromal mechanosensing affects metastasis is still unclear.
Vassilis Papalazarou +7 more
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Pancreatic ductal adenocarcinoma is particularly metastatic, with dismal survival rates and few treatment options. Stiff fibrotic stroma is a hallmark of pancreatic tumours, but how stromal mechanosensing affects metastasis is still unclear.
Vassilis Papalazarou +7 more
semanticscholar +1 more source
2007
Research has demonstrated that creatine supplementation has some therapeutic benefit with respect to muscle function and more recently neurological function. Despite the growing body of literature on the pharmacologic effect of creatine, very little is known about the disposition of creatine after supraphysiologic doses.
Wesley McCall, Adam M. Persky
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Research has demonstrated that creatine supplementation has some therapeutic benefit with respect to muscle function and more recently neurological function. Despite the growing body of literature on the pharmacologic effect of creatine, very little is known about the disposition of creatine after supraphysiologic doses.
Wesley McCall, Adam M. Persky
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Journal of Applied Physiology, 2003
The total creatine pool size [Crtotal; creatine (Cr) + phosphocreatine (PCr)] is crucial for optimal energy utilization in skeletal muscle, especially at the onset of exercise and during intense contractions. The Crtotallikely is controlled by long-term modulation of Cr uptake via the sodium-dependent Cr transporter (CrT).
Ronald L. Terjung +2 more
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The total creatine pool size [Crtotal; creatine (Cr) + phosphocreatine (PCr)] is crucial for optimal energy utilization in skeletal muscle, especially at the onset of exercise and during intense contractions. The Crtotallikely is controlled by long-term modulation of Cr uptake via the sodium-dependent Cr transporter (CrT).
Ronald L. Terjung +2 more
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Creatine and creatine forms intended for sports nutrition
Molecular Nutrition & Food Research, 2017Creatine is a popular ergogenic supplement in sports nutrition. Yet, supplementation of creatine occasionally caused adverse effects such as gastrointestinal complaints, muscle cramps and an increase in body weight. Creatine monohydrate has already been evaluated by different competent authorities and several have come to the conclusion that a daily ...
Bernd Schäfer +9 more
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Creatine in Humans with Special Reference to Creatine Supplementation
Sports Medicine, 1994Since the discovery of creatine in 1832, it has fascinated scientists with its central role in skeletal muscle metabolism. In humans, over 95% of the total creatine (Crtot) content is located in skeletal muscle, of which approximately a third is in its free (Crf) form. The remainder is present in a phosphorylated (Crphos) form. Crf and Crphos levels in
Karin Söderlund +2 more
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European Journal of Sport Science, 2018
The ergogenic and therapeutic effects of increasing muscle creatine by supplementation are well-recognized. It appears that similar benefits to brain function and cognitive processing may also be achieved with creatine supplementation, however research ...
E. Dolan, B. Gualano, E. Rawson
semanticscholar +1 more source
The ergogenic and therapeutic effects of increasing muscle creatine by supplementation are well-recognized. It appears that similar benefits to brain function and cognitive processing may also be achieved with creatine supplementation, however research ...
E. Dolan, B. Gualano, E. Rawson
semanticscholar +1 more source
CRC Critical Reviews in Clinical Laboratory Sciences, 1982
Creatine kinase is present in significant concentrations in skeletal muscle and cardiac muscle and to a lesser extent in gastrointestinal tract and brain tissue. The enzyme has been purified from a variety of tissues and an examination of its kinetic and physical properties reveal that the enzyme consists of two subunits and can exist as three ...
R, Bais, J B, Edwards
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Creatine kinase is present in significant concentrations in skeletal muscle and cardiac muscle and to a lesser extent in gastrointestinal tract and brain tissue. The enzyme has been purified from a variety of tissues and an examination of its kinetic and physical properties reveal that the enzyme consists of two subunits and can exist as three ...
R, Bais, J B, Edwards
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Creatine and Creatine Kinase in Health and Disease
2007Creatine and creatine kinase in health and disease / , Creatine and creatine kinase in health and disease / , کتابخانه دیجیتال جندی شاپور ...
Gajja S. Salomons, Markus Wyss
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