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Creatine and creatine forms intended for sports nutrition
Molecular Nutrition & Food Research, 2017Creatine is a popular ergogenic supplement in sports nutrition. Yet, supplementation of creatine occasionally caused adverse effects such as gastrointestinal complaints, muscle cramps and an increase in body weight. Creatine monohydrate has already been evaluated by different competent authorities and several have come to the conclusion that a daily ...
Bernd Schäfer +9 more
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Creatine in Humans with Special Reference to Creatine Supplementation
Sports Medicine, 1994Since the discovery of creatine in 1832, it has fascinated scientists with its central role in skeletal muscle metabolism. In humans, over 95% of the total creatine (Crtot) content is located in skeletal muscle, of which approximately a third is in its free (Crf) form. The remainder is present in a phosphorylated (Crphos) form. Crf and Crphos levels in
Karin Söderlund +2 more
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Nature Metabolism, 2019
Pancreatic ductal adenocarcinoma is particularly metastatic, with dismal survival rates and few treatment options. Stiff fibrotic stroma is a hallmark of pancreatic tumours, but how stromal mechanosensing affects metastasis is still unclear.
Vassilis Papalazarou +7 more
semanticscholar +1 more source
Pancreatic ductal adenocarcinoma is particularly metastatic, with dismal survival rates and few treatment options. Stiff fibrotic stroma is a hallmark of pancreatic tumours, but how stromal mechanosensing affects metastasis is still unclear.
Vassilis Papalazarou +7 more
semanticscholar +1 more source
Journal of Applied Physiology, 2003
The total creatine pool size [Crtotal; creatine (Cr) + phosphocreatine (PCr)] is crucial for optimal energy utilization in skeletal muscle, especially at the onset of exercise and during intense contractions. The Crtotallikely is controlled by long-term modulation of Cr uptake via the sodium-dependent Cr transporter (CrT).
Ronald L. Terjung +2 more
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The total creatine pool size [Crtotal; creatine (Cr) + phosphocreatine (PCr)] is crucial for optimal energy utilization in skeletal muscle, especially at the onset of exercise and during intense contractions. The Crtotallikely is controlled by long-term modulation of Cr uptake via the sodium-dependent Cr transporter (CrT).
Ronald L. Terjung +2 more
openaire +3 more sources
CRC Critical Reviews in Clinical Laboratory Sciences, 1982
Creatine kinase is present in significant concentrations in skeletal muscle and cardiac muscle and to a lesser extent in gastrointestinal tract and brain tissue. The enzyme has been purified from a variety of tissues and an examination of its kinetic and physical properties reveal that the enzyme consists of two subunits and can exist as three ...
R, Bais, J B, Edwards
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Creatine kinase is present in significant concentrations in skeletal muscle and cardiac muscle and to a lesser extent in gastrointestinal tract and brain tissue. The enzyme has been purified from a variety of tissues and an examination of its kinetic and physical properties reveal that the enzyme consists of two subunits and can exist as three ...
R, Bais, J B, Edwards
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Creatine and Creatine Kinase in Health and Disease
2007Creatine and creatine kinase in health and disease / , Creatine and creatine kinase in health and disease / , کتابخانه دیجیتال جندی شاپور ...
Gajja S. Salomons, Markus Wyss
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Current Sports Medicine Reports, 2013
Creatine monohydrate is a dietary supplement that increases muscle performance in short-duration, high-intensity resistance exercises, which rely on the phosphocreatine shuttle for adenosine triphosphate. The effective dosing for creatine supplementation includes loading with 0.3 g·kg·d for 5 to 7 days, followed by maintenance dosing at 0.03 g·kg·d ...
Matthew, Hall, Thomas H, Trojian
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Creatine monohydrate is a dietary supplement that increases muscle performance in short-duration, high-intensity resistance exercises, which rely on the phosphocreatine shuttle for adenosine triphosphate. The effective dosing for creatine supplementation includes loading with 0.3 g·kg·d for 5 to 7 days, followed by maintenance dosing at 0.03 g·kg·d ...
Matthew, Hall, Thomas H, Trojian
openaire +2 more sources
1982
There are two viewpoints regarding the role of the enzyme creatine Phosphokinase (CPK), which catalyzes the reversible transphosphorylation of creatine and adenine nucleotides in energy transport. The classical viewpoint (Fig. 1) regards CPK as a near equilibrium enzyme buffering cytosolic changes in nucleotide concentration (1,2), with creatine ...
Paul J. Geiger +3 more
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There are two viewpoints regarding the role of the enzyme creatine Phosphokinase (CPK), which catalyzes the reversible transphosphorylation of creatine and adenine nucleotides in energy transport. The classical viewpoint (Fig. 1) regards CPK as a near equilibrium enzyme buffering cytosolic changes in nucleotide concentration (1,2), with creatine ...
Paul J. Geiger +3 more
openaire +3 more sources
European Journal of Sport Science, 2018
The ergogenic and therapeutic effects of increasing muscle creatine by supplementation are well-recognized. It appears that similar benefits to brain function and cognitive processing may also be achieved with creatine supplementation, however research ...
E. Dolan, B. Gualano, E. Rawson
semanticscholar +1 more source
The ergogenic and therapeutic effects of increasing muscle creatine by supplementation are well-recognized. It appears that similar benefits to brain function and cognitive processing may also be achieved with creatine supplementation, however research ...
E. Dolan, B. Gualano, E. Rawson
semanticscholar +1 more source
Medicinal research reviews (Print), 2019
Creatine is pivotal in energy metabolism of muscle and brain cells, both in physiological and in pathological conditions. Additionally, creatine facilitates the differentiation of muscle and neuronal cells.
M. Balestrino, E. Adriano
semanticscholar +1 more source
Creatine is pivotal in energy metabolism of muscle and brain cells, both in physiological and in pathological conditions. Additionally, creatine facilitates the differentiation of muscle and neuronal cells.
M. Balestrino, E. Adriano
semanticscholar +1 more source