Metabolic agents that enhance ATP can improve cognitive functioning: a review of the evidence for glucose, oxygen, pyruvate, creatine, and L-carnitine. [PDF]
, 2011 Over the past four or five decades, there has been increasing interest in the neurochemical regulation of cognition. This field received considerable attention in the 1980s, with the identification of possible cognition enhancing agents or "smart drugs".
Sünram-Lea, Sandra-Ilona, Owen, Lauren
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Phosphorylation-Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia-Reperfusion. [PDF]
Adv Sci (Weinh)This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Duan C +17 more
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Effects of whey isolate, creatine and resistance training on muscle hypertrophy [PDF]
, 2007 PURPOSE: Studies that have attributed gains in lean body mass to dietary supplementation during RE training have not reported these changes alongside adaptations at the cellular and sub-cellular levels. Therefore, the purpose of this study was to examine
Carey, Michael F +4 more
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Effects of cinnamon extract supplementation on creatine kinase activity in badminton athletes [PDF]
, 2020 Purpose. Cinnamon extract, which is the result of extraction from the bark of the genus Cinnamomum, belonging to the Lauraceae family, which grows in several continents, such as Asia, Australia, and America (South America), has made researchers ...
Tirto Apriyanto +11 more
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Creatine protects against excitoxicity in an in vitro model of neurodegeneration. [PDF]
, 2012 Creatine has been shown to be neuroprotective in aging, neurodegenerative conditions and brain injury. As a common molecular background, oxidative stress and disturbed cellular energy homeostasis are key aspects in these conditions. Moreover, in a recent
Geiger Johanna +17 more
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Creatine Kinase and Blood Pressure: A Systematic Review
Medical Sciences, 2019 Background: Hypertension is a main risk factor for premature death. Although blood pressure is a complex trait, we have shown that the activity of the ATP-generating enzyme creatine kinase (CK) is a significant predictor of blood pressure and of failure ...
L. M. Brewster +2 more
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The creatine kinase system and pleiotropic effects of creatine [PDF]
Amino Acids, 2011 The pleiotropic effects of creatine (Cr) are based mostly on the functions of the enzyme creatine kinase (CK) and its high-energy product phosphocreatine (PCr). Multidisciplinary studies have established molecular, cellular, organ and somatic functions of the CK/PCr system, in particular for cells and tissues with high and intermittent energy ...
Wallimann, Theo +2 more
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Muscle Damage following Maximal Eccentric Knee Extensions in Males and Females [PDF]
, 2016 Aim: To investigate whether there is a sex difference in exercise induced muscle damage. Materials and Method: Vastus Lateralis and patella tendon properties were measured in males and females using ultrasonography.
Hicks, KM +7 more
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High Creatine Kinase (CK)-MB and Lactate Dehydrogenase in the Absence of Myocardial Injury or Infarction: A Case Report [PDF]
Journal of Cardiovascular and Thoracic Research, 2014 Acute myocardial infarction (AMI) is a life threatening condition that needs emergency diagnosis and early treatment in the emergency room. Rapid laboratory testing for creatine kinase (CK)-MB greatly revolutionized the diagnosis and management of acute ...
Nasrollah Maghamipour, Naser Safaie
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Match play performance characteristics that predict post-match creatine kinase responses in professional rugby union players [PDF]
, 2014 Background: Rugby union players can take several days to fully recover from competition. Muscle damage induced during the match has a major role in player recovery; however the specific characteristics of match play that predict post-match muscle damage ...
Harrington, Bradley J +25 more
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