This study was the largest sample size of first‐line third‐generation TKIs combined chemotherapy among advanced EGFRm NSCLC patients in the real world. It was never reported that aumolertinib and furmonertinib showed comparable PFS benefits to osimertinib in combination with chemotherapy. The overall safety profile remained acceptable. ABSTRACT FLAURA2
YuQin Jiang +9 more
wiley +1 more source
Creatine Kinase Elevations and Risk of Renal Failure and Dialysis in Patients With Rhabdomyolysis. [PDF]
Jehle DV +8 more
europepmc +1 more source
Differentiation and fiber type-specific activity of a muscle creatine kinase intronic enhancer [PDF]
Phillip W.L. Tai +9 more
openalex +1 more source
To assess the relevance of exome sequencing as a first‐tier diagnostic tool, three aspects were investigated: detection of copy number variants (CNVs) from exomes as compared to chromosomal microarray, clinically‐relevant CNVs across all sizes, and additional diagnostic utilities (uniparental disomy and triploidy).
Rivka Birnbaum +13 more
wiley +1 more source
Isotretinoin-Associated Myopathy With Normal Creatine Kinase (CK) Levels: EMG-Based Diagnosis at Low Dose-A Case Report. [PDF]
Mahyar M +4 more
europepmc +1 more source
Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy
Cerebral palsy, caused by non‐progressive brain injury, is frequently accompanied by skeletal muscle alterations. This review synthesizes current evidence from muscle biopsy studies, revealing cellular and molecular adaptations in muscle tissue. Abstract Cerebral palsy (CP), the most prevalent childhood‐onset motor disability, frequently entails ...
Sebastian Edman +4 more
wiley +1 more source
Creatine kinase B, a downstream effector of c-Myb, controls migration of osteosarcoma cells via regulation of N-cadherin. [PDF]
Pokludová J +14 more
europepmc +1 more source
Clinical role of recurrently elevated macro creatine kinase type 1 [PDF]
Ju‐Feng Hsiao +4 more
openalex +1 more source
Diabetic kidney disease, biomarkers, and finerenone
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley +1 more source
Creatine kinase and its muscle/brain isoenzyme as potential biomarkers for cardiovascular disease risk: A cross-sectional analysis of a population-based cohort. [PDF]
Izadpanah M +9 more
europepmc +1 more source

