Results 211 to 220 of about 173,452 (291)

Third‐Generation EGFR‐TKIs Combined With Chemotherapy in Advanced Non‐Small Cell Lung Cancer: A Real‐World Study

open access: yesCancer Science, EarlyView.
This study was the largest sample size of first‐line third‐generation TKIs combined chemotherapy among advanced EGFRm NSCLC patients in the real world. It was never reported that aumolertinib and furmonertinib showed comparable PFS benefits to osimertinib in combination with chemotherapy. The overall safety profile remained acceptable. ABSTRACT FLAURA2
YuQin Jiang   +9 more
wiley   +1 more source

Creatine Kinase Elevations and Risk of Renal Failure and Dialysis in Patients With Rhabdomyolysis. [PDF]

open access: yesCureus
Jehle DV   +8 more
europepmc   +1 more source

Differentiation and fiber type-specific activity of a muscle creatine kinase intronic enhancer [PDF]

open access: gold, 2011
Phillip W.L. Tai   +9 more
openalex   +1 more source

High Concordance of Copy Number Variants Detected by Chromosomal Microarray and Exome Sequencing in Clinical Diagnostics

open access: yesClinical Genetics, EarlyView.
To assess the relevance of exome sequencing as a first‐tier diagnostic tool, three aspects were investigated: detection of copy number variants (CNVs) from exomes as compared to chromosomal microarray, clinically‐relevant CNVs across all sizes, and additional diagnostic utilities (uniparental disomy and triploidy).
Rivka Birnbaum   +13 more
wiley   +1 more source

Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Cerebral palsy, caused by non‐progressive brain injury, is frequently accompanied by skeletal muscle alterations. This review synthesizes current evidence from muscle biopsy studies, revealing cellular and molecular adaptations in muscle tissue. Abstract Cerebral palsy (CP), the most prevalent childhood‐onset motor disability, frequently entails ...
Sebastian Edman   +4 more
wiley   +1 more source

Creatine kinase B, a downstream effector of c-Myb, controls migration of osteosarcoma cells via regulation of N-cadherin. [PDF]

open access: yesCancer Cell Int
Pokludová J   +14 more
europepmc   +1 more source

Clinical role of recurrently elevated macro creatine kinase type 1 [PDF]

open access: bronze, 2008
Ju‐Feng Hsiao   +4 more
openalex   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Creatine kinase and its muscle/brain isoenzyme as potential biomarkers for cardiovascular disease risk: A cross-sectional analysis of a population-based cohort. [PDF]

open access: yesPLoS One
Izadpanah M   +9 more
europepmc   +1 more source

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