Results 191 to 200 of about 164,344 (301)

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová   +12 more
wiley   +1 more source

Creatine kinase B, a downstream effector of c-Myb, controls migration of osteosarcoma cells via regulation of N-cadherin. [PDF]

open access: yesCancer Cell Int
Pokludová J   +14 more
europepmc   +1 more source

Diaphragm‐specific effects of L‐citrulline in mdx mice highlight its potential as adjuvant of standard therapy in Duchenne muscular dystrophy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The absence of the protein dystrophin in Duchenne muscular dystrophy (DMD) leads to progressive muscle weakness, failing regeneration and deregulation of nitric oxide (NO) signalling. We focused on L‐citrulline, a precursor of L‐arginine, required for NO production in muscle, which is reduced in dystrophic mdx muscle ...
Lisamaura Tulimiero   +14 more
wiley   +1 more source

Primary cardiac T‐cell rich large B‐cell lymphoma causing aortic stenosis with metastasis in a Warmblood

open access: yesEquine Veterinary Education, EarlyView.
Summary An 18‐year‐old Warmblood mare was presented to the Royal Veterinary College Equine Referral Hospital for investigation of progressive periocular and facial swelling, weight loss and tachycardia. Physical examination additionally identified bilateral pansystolic (grade 5/6 basilar left‐sided, 2/6 right‐sided), cardiac murmurs, submandibular ...
S. E. Talbot   +4 more
wiley   +1 more source

Creatine kinase and its muscle/brain isoenzyme as potential biomarkers for cardiovascular disease risk: A cross-sectional analysis of a population-based cohort. [PDF]

open access: yesPLoS One
Izadpanah M   +9 more
europepmc   +1 more source

Congenital bilateral laryngeal paralysis in a neonatal foal—Expanding our understanding of neonatal airway dysfunction

open access: yesEquine Veterinary Education, EarlyView.
Summary The case report by De Maré et al. 2025 describes a rare but instructive case of bilateral laryngeal paralysis in a newborn Warmblood foal with suspected neonatal encephalopathy (NE). The foal presented with inspiratory stridor from birth and was successfully managed through supportive medical therapy and temporary nasotracheal intubation, with ...
M. Abraham
wiley   +1 more source

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