Results 171 to 180 of about 96,822 (214)

Clinical application of subforms of creatine kinase MM and macro creatine kinases

Journal of Chromatography B: Biomedical Sciences and Applications, 1990
The subforms of MM isozyme of creatine kinase (ATP:creatine N-phosphotransferase, EC 2.7.3.2, CK) in sera obtained from healthy adults and patients were determined by agarose gel isoelectric focusing (IEF). The patients were classified into six groups according to serum CK-MM activities and IEF patterns.
F, Kanemitsu, T, Okigaki
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Brain creatine phosphate and creatine kinase in mice fed an analogue of creatine

Brain Research, 1989
Brain phosphocreatine (PCr) concentration and creatine kinase (CK) activity have been studied by 31P nuclear magnetic resonance (NMR) spectroscopy in mice fed an analogue of creatine, beta-guanidinopropionic acid (GPA). The phosphorylated analogue (GPAP), which almost completely replaces PCr in skeletal muscle, is a poor substrate for CK.
Holtzman, D, McFarland, E, Moerland, T, Koutcher, J, Kushmerick, MJ, Neuringer, LJ   +5 more
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Hybridization of matrix-bound MM-creatine kinase with BB-creatine kinase and arginine kinase

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1994
Dimeric rabbit muscle creatine kinase (MM-CK) was bound to CNBr-activated Sepharose 4B by one of its subunits (MM-CKA). Treatment of MM-CKA with guanidine hydrochloride released the unbound subunit to yield the matrix-bound monomer (M-CKB). M-CKB recombined with dissociated MM-CK soluble subunits to reconstitute a matrix-bound dimer (MM-CKC).
S R, Reddy, D C, Watts
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Elevated Creatine Kinase and Malignancy

Hospital Practice, 1990
Increased serum levels of CK isoenzymes variously signal heart, brain, or skeletal muscle damage. They may also be markers for advanced tumors with poor prognosis.
C, Eng, A E, Skolnick, S E, Come
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How to use: creatine kinase

Archives of disease in childhood - Education & practice edition, 2019
Creatine kinase (CK) remains an essential tool for assessment of muscular weakness and pain in children despite the advent of advanced diagnostic tests in this field. It is also useful in diagnosing and monitoring various other conditions. This article will explore the physiology of CK and clinical situations where the estimation of CK can help the ...
Tanmoy, Chakrabarty, Sandya, Tirupathi, Andrew, Thompson   +2 more
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The interaction of tetraiodofluorescein with creatine kinase

Biochimica et Biophysica Acta (BBA) - Enzymology, 1977
The dye 2',4',5',7'-tetraiodofluorescein is a potent inhibitor of creatine kinase (ATP:creatine N-phosphotransferase, EC 2.7.3.2) with an apparent competitive inhibition constant with respect to MgATP2- of 2.6 - 10(-5) M. The association of the dye with the enzyme elicited a red shift in the dye's spectrum, indicative of a binding site less polar than ...
L L, Somerville, F A, Quiocho
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Creatine Kinase Elevations with Clozapine

British Journal of Psychiatry, 1994
We describe a patient with marked elevations of creatine kinase following institution of clozapine treatment. The enzyme levels promptly subsided with discontinuation of clozapine. The clinical features did not meet any of the published criteria for neuroleptic malignant syndrome.
M S, Keshavan, J, Stecker, R K, Kambhampati   +2 more
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Regulation of heart creatine kinase

1987
Magnetization transfer nuclear magnetic resonance (NMR) provides measurement of the velocity of the creatine kinase reaction in the intact heart. Standard one-pulse NMR spectroscopy coupled with conventional biochemical analyses provides information about the average cytosolic concentrations of ATP, creatine phosphate (CrP), creatine (Cr) and H+ in the
J S, Ingwall, J A, Bittl
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Creatine Kinase Isoenzyme 1

Clinics in Laboratory Medicine, 1982
It is not yet clear whether creatine kinase isoenzyme 1 (CK1) fulfills ideal criteria for a tumor marker. Based on preliminary data, however, CK1 appears to be at least equal to the few markers now available.
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Scaled creatine kinase model

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1990
There was an error in one of the equations in my article entitled «Analysis of metabolic control: new insights using scaled creatine kinase model»
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