Results 181 to 190 of about 102,139 (259)

Creatine kinase and its muscle/brain isoenzyme as potential biomarkers for cardiovascular disease risk: A cross-sectional analysis of a population-based cohort. [PDF]

PLoS One
Izadpanah M, Pourahmadi E, Bana HS, Dehghani E, Akbari M, Rezae FA, Yarmohammadi F, Alnattah A, Eslami S, Taherzadeh Z.   +9 more
europepmc   +1 more source

A randomized phase 2 trial of socrodeucitinib in moderate‐to‐severe plaque psoriasis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In moderate‐to‐severe plaque psoriasis, socrodeucitinib (6 mg/12 mg) significantly outperformed placebo at week 12: PASI 75 response rates 28.6%/72.1% vs. 7.5%. Meanwhile, socrodeucitinib illustrated a favourable safety and tolerability profile, warranting further study.
Ling Han, Songmei Geng, Yangfeng Ding, Shifa Zhang, Xiaohua Wang, Fengming Hu, Jianguo Li, Chao Ci, Yayu Hu, Rixin Chen, Jianping Zhang, Xiaoyong Zhou, Aijun Chen, Chunlei Zhang, Tiechi Lei, Yanyan Feng, Yu Wang, Zudong Meng, Yan Zhou, Mingkai Ji, Wei Liu, Yunting Wu, Qianying Chen, Siyi Wang, Jinhua Xu   +24 more
wiley   +1 more source

What Are the Normal Serum Creatine Kinase Values for Skeletal Muscle? A Worldwide Systematic Review. [PDF]

Eur J Neurol
Aleksovska K, Kyriakides T, Angelini C, Argov Z, Claeys KG, de Visser M, Filosto M, Jovanovic I, Kostera-Pruszczyk A, Molnar MJ, Sacconi S, Schaefer J, Siciliano G, Vilchez JJ, Toscano A, Schoser B.   +15 more
europepmc   +1 more source

AI‐Assisted Literature Mining Reveals Spatiotemporal Heterogeneity and Progression Trajectories of Traditional Chinese Medicine Syndromes in Coronary Heart Disease in China

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Despite the centrality of syndrome differentiation in guiding personalized traditional Chinese medicine (TCM) interventions for coronary heart disease (CHD), existing studies of TCM syndrome distribution are constrained by fragmented methodologies and limited spatiotemporal resolution. In this study, we employed an artificial intelligence (AI)‐
Qianzi Che, Tian Song, Zhaoyuan Gong, Chuxuan Wang, Bin Liu, Mingzhi Hu, Ning Liang, Haili Zhang, Huizhen Li, Qingyang Zeng, Lin Chen, Yuanming Leng, Xihao Cao, Jing Wan, Jing Guo, Nannan Shi   +15 more
wiley   +1 more source

Retrospective Evaluation of the Severity of Creatine Kinase Elevation in Canine and Feline Trauma Patients as a Predictor of Morbidity and Mortality. [PDF]

Vet Med (Auckl)
Hurst O, Mastrocco A, Prittie J, Hadala A, Weltman JG.   +4 more
europepmc   +1 more source

Treatment Goals for Primary Biliary Cholangitis, an Australian Perspective

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Primary biliary cholangitis (PBC) is an autoimmune liver disease that targets the small intrahepatic bile ducts with diagnosis based on elevated serum alkaline phosphatase (ALP) levels and the presence of anti‐mitochondrial antibodies. Untreated, it may run a progressive course to cirrhosis and hepatic decompensation, at which point liver ...
Simone I. Strasser, Alexander J. Thompson, Rohit Gupta, John Lubel, Janine French, Beverly Sacks, Martin Weltman   +6 more
wiley   +1 more source

Creatine Kinase as a Predictor of Disease Severity in Children with COVID-19. [PDF]

Med J Islam Repub Iran
Nateghian A, Nojomi M, Roohravan Benis M, Heidarpour T.   +3 more
europepmc   +1 more source

Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis

Journal of Integrative Plant Biology, EarlyView.
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia, Medha Noopur, Ishana Bhattacharya, Bhaskar Chandra Sahoo, Mritunjay Kasera, Naga Jyothi Pullagurla, Smritikana Dutta, Guizhen Liu, Gabriel Schaaf, Henning Jessen, Debabrata Laha, Souvik Bhattacharjee, Saikat Bhattacharjee   +12 more
wiley   +1 more source

Systemic mitochondrial involvement in mitochondrial myopathy with episodic hyper-creatine kinase-emia: insights from an autopsy case. [PDF]

J Neurol
Nagatomo R, Hiramatsu Y, Sakiyama Y, Miyahara H, Nasu T, Yamazaki I, Yoshimura A, Ando M, Nozuma S, Higuchi Y, Akagi A, Iwasaki Y, Yuan JH, Okamoto Y, Takashima H.   +14 more
europepmc   +1 more source

Guanidinoacetic Acid Improves Growth Performance and Gut Health of Broilers Fed Metabolizable Energy‐Reduced Diets

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study was conducted to evaluate the effects of guanidinoacetic acid (GAA) supplementation to diets with different energy levels on growth performance, carcass traits, and gut health status in broiler chickens. A total of 9500 1‐day‐old Ross 308 broilers (equal numbers of males and females) were allocated to 1 of 5 dietary treatments (10 ...
Necmettin Ceylan, Ali Anıl Çenesiz, İsmail Yavaş, Sait Koca, Vivienne Inhuber   +4 more
wiley   +1 more source