Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo +4 more
wiley +1 more source
Systemic mitochondrial involvement in mitochondrial myopathy with episodic hyper-creatine kinase-emia: insights from an autopsy case. [PDF]
Nagatomo R +14 more
europepmc +1 more source
Long‐term effects of crizotinib in ALK‐positive tumors (excluding NSCLC): A phase 1b open‐label study [PDF]
et al, +2 more
core +1 more source
Meta‐analysis of randomized controlled trials demonstrates that oral icotrokinra significantly improves PASI responses in patients with moderate‐to‐severe plaque psoriasis, with early clinical benefit and a placebo‐comparable safety profile, supported by trial sequential analysis confirming robust and sufficient evidence.
Alhasan Altayf +5 more
wiley +1 more source
Creatine Kinase as a Predictor of Disease Severity in Children with COVID-19. [PDF]
Nateghian A +3 more
europepmc +1 more source
Unexplained Elevated Vitamin B12: Consider Macro‐B12
ABSTRACT Introduction Elevated vitamin B12 concentration can be caused by supplementation, liver disease, kidney disease, or myeloid malignancies. Persistent, unexplained elevations of vitamin B12 can raise concern among patients and may lead to invasive diagnostic procedures, including bone marrow biopsy.
Evelien G. E. Hurkmans +3 more
wiley +1 more source
Seasonal Trends in Cardiac Troponin I Concentration and Creatine Kinase and Aspartate Aminotransferase Enzyme Activity in Relation to Myocardial Velocity Rates in Eventing Horses. [PDF]
Rump-Dierig I +4 more
europepmc +1 more source
Comparison of HEMOlysis Markers Among Three Pulsed Field Ablation Systems: HEMO‐PFA Study
ABSTRACT Background Pulsed field ablation (PFA) has emerged as a novel non‐thermal modality for atrial fibrillation (AF) ablation. While hemolysis is a known complication of PFA, comparative data among different systems remain limited. Methods We prospectively enrolled 150 consecutive AF patients undergoing ablation with one of three PFA systems ...
Kazuhisa Matsumoto +11 more
wiley +1 more source
French guidelines on systemic treatments for moderate‐to‐severe psoriasis in adults: Update 2025
New 2025 French guidelines update psoriasis management with revised algorithms integrating recent systemic therapies. They recommend methotrexate, adalimumab or ustekinumab as first‐line treatments and provide guidance for special psoriasis forms, comorbidities, pregnancy and long‐term management.
Marie Masson Regnault +51 more
wiley +1 more source
Phosphocreatine Rescues Intestinal Epithelial Metabolic Dysfunction Related to Creatine Kinase Loss and Is Protective in Murine Colitis. [PDF]
Bhagavatula G +8 more
europepmc +1 more source

