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Creatine Kinase Isoenzymes

Clinics in Laboratory Medicine, 1986
Creatine kinase (CK), a widely distributed enzyme in the body, has its highest activities in skeletal muscle and myocardium; when serum CK activities are abnormally increased, injury to these organs must be part of the differential diagnosis. The isoenzyme CK-MB is the most important biochemical test in the diagnosis of acute myocardial infarction.
J A, Lott, L B, Abbott
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Investigating raised creatine kinase

BMJ, 2021
A 76 year old man with hypercholesterolaemia is referred to the lipid clinic because of persistently raised creatine kinase activity of 1000 IU/L or above (reference range 40-320 IU/L) after trying multiple statins. He describes no significant myalgia but had some proximal muscle weakness, which is demonstrated when he stands up from a seated position ...
Eun Ji, Kim, Anthony S, Wierzbicki
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Creatine, Creatine Kinase, and Aging

2018
With an ever aging population, identifying interventions that can alleviate age-related functional declines has become increasingly important. Dietary supplements have taken center stage based on various health claims and have become a multi-million dollar business.
Nathalie, Sumien   +2 more
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Creatine Kinase Levels

Archives of Internal Medicine, 1982
To the Editor. —I read with interest the article by Dillon et al entitled "Diagnostic Problem in Acute Myocardial Infarction: CK-MB in the Absence of Abnormally Elevated Total Creatine Kinase Levels" published in the JanuaryArchives(1982;142:33-38).
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Evolution of Creatine Kinase

Nature, 1967
Comparison of the electrophoretic patterns of creatine kinase in different birds throws some light on the type of evolutionary changes which have affected the multiple forms of this enzyme.
M E, Eppenberger   +2 more
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Macro‐creatine kinase: a neglected cause of elevated creatine kinase

Internal Medicine Journal, 2015
AbstractMacro‐creatine kinase (macro‐CK) is a neglected cause of raised CK. Over a 10‐year period, we observed five cases. Three patients had macro‐CK type 1. One patient with fibromyalgia underwent several explorations to find a muscular pathology; another, who had elevated CK‐MB (muscle–brain fraction) activity, was referred to a cardiologist, and ...
F, Aljuani   +4 more
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CREATINE KINASE AND CREATINE KINASE ISOENZYME RESPONSES TO HEAT STRESS

Cell Biology International, 1998
AbstractDuring this investigation the effects of heat acclimation and exercise on creatine kinase and creatine kinase BB isoenzyme responses in various tissues and serum of male Sprague—Dawley rats were ascertained. Forty rats were randomly divided into two groups of 20 rats each. One group was housed at 22±1°C and the other at 33±1°C.
S E, Terblanche, W, Nel
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Creatine kinase and creatine kinase-MB release after nontraumatic cardiac arrest

Resuscitation, 1996
The aim of the study was to describe the course of serum creatine kinase (CK) and its MB fraction (CK-MB) in patients surviving cardiac arrest, and to identify factors influencing CK and CK-MB release. The study was set in the community of Vienna, Austria.
M, Müllner   +9 more
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Scaled creatine kinase model

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1990
There was an error in one of the equations in my article entitled «Analysis of metabolic control: new insights using scaled creatine kinase model»
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Creatine Kinase Isoenzyme 1

Clinics in Laboratory Medicine, 1982
It is not yet clear whether creatine kinase isoenzyme 1 (CK1) fulfills ideal criteria for a tumor marker. Based on preliminary data, however, CK1 appears to be at least equal to the few markers now available.
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