Results 281 to 290 of about 169,068 (339)

Creation of Genetically Modified Adipocytes for Tissue Engineering: Creatine Kinase B Overexpression Leads to Stimulated Glucose Uptake and Mitochondrial Potential Growth, but Lowered Lipid Synthesis. [PDF]

Life (Basel)
Michurina S, Beloglazova I, Agareva M, Alekseeva N, Parfyonova Y, Stafeev I.   +5 more
europepmc   +1 more source

Modelling the effect of varying metabolic rate and cardiac output on estimated tissue and blood O2 and CO2 levels in an extreme deep‐diver, the goose‐beaked whale (Ziphius cavirostris)

Experimental Physiology, EarlyView.
Abstract High‐resolution movement data from Cuvier's beaked, or goose‐beaked whale (Ziphius cavirostris, hereafter Ziphius, n = 8) tag deployments (4.1–19.2 days) were used to estimate blood and tissue O2 and CO2 levels. Acceleration and magnetometry data were used to estimate the locomotion cost (LC) from the relationship between activity and the O2 ...
Andreas Fahlman, Gregory S. Schorr, David A. Sweeney, Brenda K. Rone, Shannon N. Coates, Austin S. Allen, Lucia M. Martín López, Susan M. Jarvis, Erin A. Falcone   +8 more
wiley   +1 more source

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

Experimental Physiology, EarlyView.
Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su, Na Liu, Yang Liu, Yiqun Sun, Yike Jiao   +4 more
wiley   +1 more source

The repair capacity spectrum of human skeletal muscle injury from sports to surgical trauma settings

The Journal of Physiology, EarlyView.
Abstract figure legend The interplay between current knowledge, treatment strategies and remaining unsolved clinical challenges in optimising clinical outcomes for patients suffering skeletal muscle tissue injury. In particular the outcome for strain injuries and acute extremity compartment syndrome remains poor, despite extensive work in animal models.
Grith Højfeldt, Christian Hoegsbjerg, Arvind G. von Keudell, Abigail L. Mackey   +3 more
wiley   +1 more source

Muscle regeneration is improved by hot water immersion but unchanged by cold following a simulated musculoskeletal injury in humans

The Journal of Physiology, EarlyView.
Abstract figure legend Thirty‐four participants underwent muscle damage (electrically stimulated eccentric contractions) triggering regenerative processes following myofiber necrosis. Participants were treated for 10 days cold (CWI) (15 min, 12{degree sign}C), thermoneutral (TWI) (30 min, 32{degree sign}C) or hot (HWI) (60 min, 42{degree sign}C) water ...
Valentin Dablainville, Adèle Mornas, Tom Normand‐Gravier, Maha Al‐Mulla, Emmanouil Papakostas, Bruno Olory, Theodorakys Marin Fermin, Frantzeska Zampeli, Nelda Nader, Marine Alhammoud, Freya Bayne, Anthony M. J. Sanchez, Marco Cardinale, Robin Candau, Henri Bernardi, Sébastien Racinais   +15 more
wiley   +1 more source

Mitochondrial Creatine Kinase 2 (Ckmt2) as a Plasma-Based Biomarker for Evaluating Reperfusion Injury in Acute Myocardial Infarction. [PDF]

Biomedicines
Lang A, Oehler D, Benkhoff M, Reinders Y, Barcik M, Shahrjerdi K, Kaldirim M, Sickmann A, Dannenberg L, Polzin A, Pfeiler S, Kelm M, Grandoch M, Jung C, Gerdes N.   +14 more
europepmc   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

A case control study of the relationship between persistent serum creatine kinase elevation and polyneuropathy. [PDF]

Sci Rep
Bekkelund SI, Abeler K, Lilleng H, Løseth S.   +3 more
europepmc   +1 more source

Catecholaminergic polymorphic ventricular tachycardia–linked ryanodine receptor variants exhibit domain‐specific calcium leak and calmodulin affinity properties

The Journal of Physiology, EarlyView.
Abstract figure legend Catecholaminergic polymorphic ventricular tachycardia (CPVT) variants in N terminal (NTD) and central domain (CD) but not pore domain induce a pathological RyR2 conformational shift upon protein kinase A (PKA) phosphorylation, similar to that seen in heart failure (HF), calcium/calmodulin‐dependent protein kinase II (CaMKII ...
Hitoshi Uchinoumi, Xiaoqiong Dong, Ivanita Stefanon, Yi Yang, Eduardo Hertel Ribeiro, Bengt Svensson, Xander H. T. Wehrens, Takeshi Yamamoto, Razvan L. Cornea, Robyn T. Rebbeck, Masafumi Yano, Donald M. Bers   +11 more
wiley   +1 more source

Surgical Improvement of Neuropathy-Induced Calf Muscle Hypertrophy and Creatine Kinase Elevation: A Case Report. [PDF]

Cureus
Fukuda M, Ohtake Y, Hiratsuka Y, Ishizuka T, Nakamura H.   +4 more
europepmc   +1 more source