Results 321 to 330 of about 1,019,575 (429)

Slowly Progressive Rhabdomyolysis Post COVID-19: Insights for Acute Kidney Injury Prediction With Discordant Creatine Kinase and Myoglobin Elevations. [PDF]

Cureus
Okubo T, Kouzu H, Kamada A, Endo K, Kawaharata W, Ohwada W, Suda K, Nagano N, Sakurai A, Koyama M, Furuhashi M.   +10 more
europepmc   +1 more source

DIAGNOSTIC SIGNIFICANCE OF SERUM CREATINE KINASE ISOENZYME, MB FRACTION (CK-MB) IN ACUTE MYOCARDIAL INFARCTION

, 1978
Hojyo Yuu
openalex   +2 more sources

JAK–STAT inhibitory effect of IN‐115314, a novel small molecule inhibitor, and pharmacokinetic/pharmacodynamic study in canine

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The JAK–STAT signalling pathway has been extensively spotlighted as a therapeutic target for various diseases. This study assessed the inhibitory effects of a novel small molecule, IN‐115314, on JAK–STAT pathway. Experimental Approach The IC50 values of IN‐115314 for JAK1–pSTAT3 and JAK2–pSTAT5 were determined in canine ...
Jae‐Hun Ahn, Joohwan Kim, Jina Kwak, Jooil Kim, Na‐Young Lee, Heejin Choi, Hee‐Jin Bae, So‐Hyun Cho, Sung‐Gu Jung, Hye‐Mi Kwon, Euna Kwon, Donghyun Kim, Myeongjoong Kim, Daseul Yoon, Seohyun Kim, Bongtae Kim, Byeong‐Cheol Kang   +16 more
wiley   +1 more source

Maintaining energy provision in the heart: the creatine kinase system in ischaemia-reperfusion injury and chronic heart failure. [PDF]

Clin Sci (Lond)
Lygate CA.
europepmc   +1 more source

In Vivo Inhibition of Grey Partridge (Perdrix Perdrix) Creatine-Kinase by Methoxy Ethyl Mercury Silicate

, 1977
A.G. Rico, J.P. Braun, P. Bénard, V. Burgat‐Sacaze   +3 more
openalex   +1 more source

CAR‐T Cell Therapy in Autoimmune Setting: A New Appealing Approach Extendable to Allergy?

Allergy, EarlyView.
Federico Rossi, Rubén Fernandez Santamaria, Riccardo Castagnoli   +2 more
wiley   +1 more source

Significance of detecting cardiac troponin I and creatine kinase MB in critically Ill children without primary cardiac illness. [PDF]

Front Pediatr
Zhang Y, Cao Y, Xin Y, Liu Y.
europepmc   +1 more source

Research‐Based Whole Genome Sequencing Identifies Biallelic Loss of Function Variants in DOCK3 Gene Causing DOCK3‐Related Disorder: The End of a Diagnostic Journey for This Family

Clinical Genetics, EarlyView.
ABSTRACT The DOCK3 gene (NM_004947.5) is located on chromosome 3p21.2 spanning 53 exons and encodes the dedicator of cytokinesis 3 protein. DOCK3 belongs to the family of guanine nucleotide exchange factors (GEFs) that activate GTPases. DOCK3 is expressed almost exclusively in the central nervous system and has been shown to promote axonal outgrowth ...
Khurram Liaqat, Kayla Treat, Lili Mantcheva, Aaron McLaughlin, Amy Breman, Molly McPheron, Erin Conboy, Francesco Vetrini   +7 more
wiley   +1 more source

Feasibility of aligning creatine kinase MB activity and mass data in multicentre trials using generalized additive modelling. [PDF]

Interdiscip Cardiovasc Thorac Surg
Hoenicka M, Vokshi A, Zhou S, Liebold A, Mayer B.   +4 more
europepmc   +1 more source

Infantile Cerebellar‐Retinal Degeneration Associated With Novel ACO2 Variants: Clinical Features and Insights From a Drosophila Model

Clinical Genetics, EarlyView.
Our Translational Loop integrates patient genetic data with Drosophila models to study disease mechanisms. We identified ACO2 variants in a patient linked to ICRD and show that our animal model mirrors key aspects of the disease. These insights help pinpoint therapeutic targets, advancing research toward treatments for rare genetic disorders.
Edgar Buhl, Suchika Garg, Marie Monaghan, Amy Preston, Marcus Likeman, Julianne Dare, Julie Evans, Lucie S. Taylor, Ian Berry, Kathryn Urankar, Paul G. D. Spry, Cathy Williams, Robert W. Taylor, Charlotte L. Alston, James J. L. Hodge, Anirban Majumdar   +15 more
wiley   +1 more source