Results 71 to 80 of about 164,344 (301)

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

SLC6A8-mediated creatine uptake suppresses ERK2-FSP1 signaling and induces ferroptosis in colorectal cancer

Cell Reports
Summary: Tumor metabolic reprogramming is critical for providing energy to support proliferation and resistance to stress-induced cell death. However, the regulatory mechanisms linking these processes remain incompletely understood.
Xiaojun Zhou, Genxin Wang, Yuhang Wu, Mingzhi Wu, Xiang Zhai, Chenhui Tian, Edward V. Prochownik, Congqing Jiang, Youjun Li   +8 more
doaj   +1 more source

The effect of estrogen on muscle damage biomarkers following prolonged aerobic exercise in eumenorrheic women

Biology of Sport, 2015
This study assessed the influence of estrogen (E 2 ) on muscle damage biomarkers [skeletal muscle - creatine kinase (CK); cardiac muscle - CK-MB] responses to prolonged aerobic exercise.
T Williams, E Walz, AR Lane, M Pebole, AC Hackney   +4 more
doaj   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Effects of transporting bulls at different space allowances on physiological, haematological and immunological responses to a 12-h journey by road [PDF]

, 2006
peer-reviewedThe effects of space allowance during transportation on physiological, haematological and immunological responses in nine-month old bulls (250 kg) were assessed before and after a 12-h road journey.
Earley, Bernadette, O'Riordan, Edward G.
core  

Differences in leukocyte profile, gene expression, and metabolite status of dairy cows with or without sole ulcers [PDF]

, 2014
peer-reviewedSole ulcers are one of the most severe pathologies causing lameness in dairy cows and are associated with abnormal behavior and impaired production performance.
Aggarwal, Almeida, Almeida, Alsemgeest, Apple, Arya, Bernadette Earley, Bicalho, Bicalho, Buckham Sporer, Buckham-Sporer, Burton, Chao, Chen, Cooray, Davis, Derveaux, Fell, Fujishima, Galyean, Godson, Hart, Hellemans, Janeway, Jawor, Kansas, Keelin O’Driscoll, Knott, Kossaibati, Kulberg, Leeman, Lischer, Lischer, Matthew McCabe, McDowell, Moore, Murray, Nagata, Nocek, Opal, O’Driscoll, O’Driscoll, O’Driscoll, O’Loughlin, Preisler, Radostits, Rider, Shi, Smith, Tadich, Tarlton, Thoefner, Tomlinson, Watkins, Weber, Weber, Weissman, Whay, Whay, Wigmore   +59 more
core   +1 more source

Multisystem proteinopathy due to a homozygous p.Arg159His VCP mutation : a tale of the unexpected [PDF]

, 2020
ObjectiveTo assess the clinical, radiologic, myopathologic, and proteomic findings in a patient manifesting a multisystem proteinopathy due to a homozygous valosin-containing protein gene (VCP) mutation previously reported to be pathogenic in the ...
Azmi, A, Baets, J, Clemen, CS, De Bleecker, Jan, De Jonghe, P, De Ridder, W, Eichinger, L, Hofmann, A, Johnson, K, Maudsley, S, Schröder, R, Straub, V, Töpf, A   +12 more
core   +1 more source

Psoas Muscle Volume as a Predictor of Postoperative Complications in Patients Undergoing Emergency Surgery for Strangulated Small Bowel Obstruction: A Retrospective Single‐Center Study

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study identified low preoperative psoas muscle volume, measured by computed tomography, as an independent predictor of postoperative complications in patients undergoing emergency surgery for strangulated small bowel obstruction. Low psoas muscle volume, particularly in older adults, was associated with cardiopulmonary and systemic ...
Takuya Shiraishi, Chika Katayama, Yuta Shibasaki, Chika Komine, Takuhisa Okada, Akihiko Sano, Makoto Sakai, Hiroomi Ogawa, Ken Shirabe, Hiroshi Saeki   +9 more
wiley   +1 more source

Recent Trends in Metabolomics by NMR Spectroscopy

Angewandte Chemie, EarlyView.
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco, Gaia Meoni, Veronica Ghini, Alessia Vignoli, Leonardo Tenori, Paola Turano, Claudio Luchinat   +6 more
wiley   +2 more sources

Increased postictal creatine kinase in epilepsy patients

Эпилепсия и пароксизмальные состояния
Excessive muscle activity during generalized convulsive seizures in epilepsy patients in some cases can cause significant changes in blood plasma biochemical parameters, increased level of a set of metabolites, particularly, serum creatine kinase ...
L. V. Lipatova, I. V. Sakovsky
doaj   +1 more source