Results 91 to 100 of about 960,906 (340)

Effect of storage time and temperature on serum analytes [PDF]

, 2008
Information on the measured concentration of serum analytes during storage of serum samples is often incomplete and sometimes contradictory. The 10 analytes have not studied in this area in healthy subjects.
Marjani, A.
core   +1 more source

Worsening renal function and outcome in heart failure patients with reduced and preserved ejection fraction and the impact of angiotensin receptor blocker treatment: data from the CHARM-study programme [PDF]

, 2016
Aims We investigated the association between worsening renal function (WRF) that occurs during renin–angiotensin–aldosterone system inhibition initation and outcome in heart failure (HF) patients with preserved ejection fraction (HFPEF) and compared ...
Brenner, Clark, Damman, Damman, Damman, Hillege, Lesogor, Lewis, Lindenfeld, Massie, McAlister, McMurray, National Institute for Health and Clinical Excellence, Pfeffer, Rossignol, Rossignol, Rusinaru, Swedberg, Testani, Vardeny, Yancy, Yusuf   +21 more
core   +1 more source

Integrin β4‐Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma

Advanced Healthcare Materials, EarlyView.
The expression of integrin β4 (ITGβ4) on small extracellular vesicle (sEV) correlates with lung‐tropism. Enrichment of ITGβ4 on sEVs enhances their lung‐targeting ability. The sEVs loaded with doxorubicin exhibit superior therapeutic efficacy in a lung metastasis mouse model.
Tung Him Ng, Aijun Liang, Maximus CF Yeung, Sze Keong Tey, Kam‐Leung Siu, Sin‐Yee Fung, Dong‐Yan Jin, Judy Wai Ping Yam   +7 more
wiley   +1 more source

How to improve drug dosing for patients with renal impairment in primary care - a cluster-randomized controlled trial [PDF]

, 2012
Background: Patients with chronic kidney disease (CKD) are at increased risk for inappropriate or potentially harmful prescribing. The aim of this study was to examine whether a multifaceted intervention including the use of a software programme for the ...
Beyer, Martin, Erler, Antje, Gerlach, Ferdinand M., Haefeli, Walter E., Petersen, Juliana, Rath, Thomas, Rochon, Justine, Saal, Kristina   +7 more
core   +1 more source

Study of Serum urea and Creatinine in Diabetic and non-diabetic patients in in a tertiary teaching hospital

The Journal of medical research, 2016
Introduction: Diabetes is on the rise worldwide and India has more number of diabetics with more than 60 million people diagnosed to suffer from the disease in 2013. Approximately 20% to 30% of all diabetics will develop evidence of nephropathy, although
S. Bamanikar, A. Bamanikar, A. Arora
semanticscholar   +1 more source

Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics

Advanced Healthcare Materials, EarlyView.
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam, Xiaoqi Wang, Grace Chung Yan Chan, Wai Po Kong, Wai Yin Chau, Xiuqiong Fu, Kwok‐Yin Wong, Hong Lok Lung, Zhi‐Ling Yu, Wei Shen Aik   +9 more
wiley   +1 more source

The Effect of Mannitol Treatment on Renal Functions in Acute Stroke

Türk Nöroloji Dergisi, 2010
OBJECTIVE: Mannitol is an osmotic diuretic agent and reduces intracranial pressure. The most serious side effect of mannitol is kidney dysfunction. In this study, renal functions in acute stroke patients treated with mannitol were evaluated.
Neslihan Eşkut, Çağla Filiz, Ufuk Şener, Metin Murat Özçelik, Nazif Çalış, Yaşar Zorlu   +5 more
doaj  

Reference intervals for urinary cotinine levels and the influence of sampling time and other predictors on its excretion among italian schoolchildren [PDF]

, 2018
(1) Background: Environmental Tobacco Smoke (ETS) exposure remains a public health problem worldwide. The aims are to establish urinary (u-) cotinine reference values for healthy Italian children, to evaluate the role of the sampling time and of other ...
Andreoli, Roberta, Avino, Pasquale, Manigrasso, Maurizio, Mutti, Antonio, Protano, Carmela, Vitali, Matteo   +5 more
core   +2 more sources

Selective Lipolysis by Photoactivation of Chaperone‐Mediated Autophagy Using Adipocyte Membrane‐Coated Nanoparticle in Hydrogel

Advanced Materials, EarlyView.
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi, Junho Byun, Dongyoon Kim, Qiaoyun Li, Dongun Jin, Yeong‐jin Choi, Ho Sang Jung, Jaiwoo Lee, Yu‐Kyoung Oh   +8 more
wiley   +1 more source

Spot urine sodium‐to‐creatinine ratio surpasses sodium in identifying poor diuretic response in acute heart failure

ESC Heart Failure
Aims We aim to identify the most accurate marker for early prediction of poor diuretic response in acute heart failure (AHF) patients with signs of congestion requiring intravenous diuretic treatment.
Gracjan Iwanek, Mateusz Guzik, Robert Zymliński, Marat Fudim, Piotr Ponikowski, Jan Biegus   +5 more
doaj   +1 more source