Results 121 to 130 of about 641,322 (293)
Advanced Science, EarlyView.Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng +10 more
wiley +1 more source
Advanced Science, EarlyView.Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha +4 more
wiley +1 more source
Automatic Reporting of Creatinine-Based Estimated Glomerular Filtration Rate in Children: Is this Feasible? [PDF]
, 2016 Creatinine, although widely used as a biomarker to measure renal function, has long been known as an insensitive marker of renal impairment. Patients with reduced renal function can have a creatinine level within the normal range, with a rapid rise when ...
Andrew Lunn
core
Advanced Science, EarlyView.USP10 binds to and stabilizes PFKFB4, enhancing glycolytic ATP production, which activates the urea cycle and elevates fumarate. This inhibits histone demethylase KDM1A, leading to increased H3K4me1 enrichment at the Rad51 promoter and direct activation of Rad51 transcription, which confers lung cancer radioresistance. The PFKFB4 inhibitor 5MPN targets
Yunshang Chen +7 more
wiley +1 more source
Montmorillonite adsorbs creatinine and accelerates creatinine excretion from the intestine
, 2009 Objectives This study aims to evaluate the sorption by montmorillonite of creatinine and the accelerating effect of montmorillonite on creatinine excretion from the intestine. Methods
Li-hui Long +4 more
core +1 more source
Advanced Science, EarlyView.The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang +8 more
wiley +1 more source
یافتههای نوین در علوم زیستی, 2020 Gentamicin (GM) is an antibiotic widely used against gram-negative infections. However, its clinical application is limited due to its nephrotoxicity. Oxidative stress plays an important role in the nephrotoxicity of gentamicin.
Siamak Yari +3 more
doaj
, 1984 dissertationCreatinine clearance is used as a measure of renal function and is useful for initiation and alteration of dosages of renally excreted drugs.
Dees, Debra Nemeth
core
Advanced Science, EarlyView.Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi +14 more
wiley +1 more source
DEVELOPMENT OF CREATININE-SENSITIVE BIOSENSOR BASED ON IMMOBILIZED CREATININE DEIMINASE [PDF]
Aim.Thе purpose of the work was to develop a new construction of enzyme biosensor based on creatinine deiminase for highly sensitive creatinine determination. Methods.
V.M. ARKHYPOV +3 more
core +2 more sources