Results 131 to 140 of about 1,066,377 (393)

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

THE STABILITY OF CREATININE, UREA, AND URIC ACID IN SAMPLES STORED AT DIFFERENT PREDEFINED STORAGE CONDITION

open access: diamond, 2021
Mariam Abbas   +9 more
openalex   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang   +32 more
wiley   +1 more source

Novel Algorithm to Estimate Fat‐Free Muscle Volumes in Women Using the Urinary Deuterated‐Creatine Dilution Method

open access: yesJournal of Cachexia, Sarcopenia and Muscle
Background Muscle mass declines after menopause and is a key risk factor for frailty, falls and poor physical function as women age. The deuterated creatine (D3Cr) dilution method provides a direct assessment of muscle mass, but its accuracy in Asian ...
Darren Yuen Zhang Tan   +6 more
doaj   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

open access: yesAdvanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang   +10 more
wiley   +1 more source

The Price-Quality Paradox in Healthcare [PDF]

open access: yes, 2016
This data brief compares average state-level prices against quality measures for asthma, diabetes and hypertension care and finds that higher prices for medical services are not always indicative of higher quality of ...
Eric Barrette, Kevin Kennedy
core  

Salivary creatinine and urea analysis in patients with chronic kidney disease: a case control study

open access: yesBMC Nephrology, 2016
BackgroundMany metabolic changes develop in patients with chronic kidney disease which often necessitate frequent biochemical analysis of blood. Saliva analysis as an alternative to blood has many advantages.
T. J. Lasisi, Y. Raji, B. Salako
semanticscholar   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

open access: yesAdvanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu   +18 more
wiley   +1 more source

Present Situation and Research Progress of Kidney Function Recoverability Evaluation of Acute Kidney Injury Patient

open access: yesInternational Journal of General Medicine, 2021
Yu-Long Yao, Yuan Gao Department of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People’s Republic of ChinaCorrespondence: Yuan GaoDepartment of Critical Care Medicine, Renji Hospital,
Yao YL, Gao Y
doaj  

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