Results 161 to 170 of about 485,256 (293)

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source

A simple formula for predicting the warfarin dose in atrial fibrillation: development, external validation, and model comparison. [PDF]

Thromb J
Ujjin A, Pongbangli N, Wongcharoen W, Suwanagool A, Chai-Adisaksopha C.   +4 more
europepmc   +1 more source

MICROMETHODS FOR DETERMINATION OF AMMONIA, UREA, TOTAL NITROGEN, URIC ACID, CREATININE (AND CREATINE), AND ALLANTOIN

, 1935
Henry Borsook
openalex   +1 more source

The Endogenous Creatinine Clearance in Normal Subjects [PDF]

, 1954
Margaret Honora Roscoe
openalex   +1 more source

Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells‐Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation

Advanced Science, EarlyView.
This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li, Maoxiang Xu, Boyu Cai, Xiangyu Li, Zhanping Liang, Xiaohuan Xia, Haitao Zhang, Zhiwen Zhang, Fei Tan, Jialin Charlie Zheng   +9 more
wiley   +1 more source

Impact of Muscle Mass on the Performance of Creatinine-Based eGFR Equations and Mortality Risk Assessment After Kidney Transplantation. [PDF]

J Cachexia Sarcopenia Muscle
Gaillard F, Rabah MO, Aubert O, Garcelon N, Neuraz A, Legendre C, Anglicheau D, Prié D, Bienaimé F.   +8 more
europepmc   +1 more source

THE PRODUCTION OF BACTERIAL ENZYMES CAPABLE OF DECOMPOSING CREATININE

, 1937
René Dubos, Benjamin F. Miller
openalex   +1 more source

Utilizing Proteolytic‐Resistant Nano‐Short Peptide Based on Naphthyl Tail‐Anchored to Combat Bacterial Infections

Advanced Science, EarlyView.
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan, Yinfeng Lyu, Yi Liu, Jianping Ren, Yue Zhao, Licong Zhang, Anshan Shan   +6 more
wiley   +1 more source

Screening Using Chronic Kidney Disease Epidemiology Collaboration 2021 Equation Glomerular Filtration Rate Underestimates in Living Kidney Donors Compared With Measurement of Glomerular Filtration Rate. [PDF]

Transplant Direct
Quintiliano A, Schreiner TB, Garcia Valencia OA, Balakrishnan S, Issa N, Schinstock CA, Riad SM, Kukla A, Larson TS, Bentall AJ.   +9 more
europepmc   +1 more source

INULIN AND CREATININE CLEARANCES IN DOGS, WITH NOTES ON SOME LATE EFFECTS OF URANIUM POISONING

, 1936
A. N. Richards, B. B. Westfall, P. A. Bott   +2 more
openalex   +1 more source