Results 211 to 220 of about 751,137 (338)

Development of Age‐ and Sex‐Specific Metabolomics‐Based Biological Ageing Clocks for 10‐Year Mortality Prediction

open access: yesAdvanced Science, EarlyView.
Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng   +4 more
wiley   +1 more source

Critical analysis of the estimated glomerular filtration rate. [PDF]

open access: yesJ Bras Nefrol
Kirsztajn GM   +3 more
europepmc   +1 more source

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie   +18 more
wiley   +1 more source

SOME APPLICATIONS OF A NEW COLOR REACTION FOR CREATININE

open access: hybrid, 1936
Stanley R. Benedict   +1 more
openalex   +1 more source

GLM7 – A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity

open access: yesAdvanced Science, EarlyView.
This study leverages NHANES data to analyze 49 routine indicators, identifying the top 10 diagnostic markers for five major diseases and introducing GLM7, a novel indicator. Restricted cubic spline analyses, forest plot evaluations, and XGBoost modeling demonstrate conventional indicators' efficacy and GLM7's value for disease diagnosis/prediction ...
Zhihua Wang   +8 more
wiley   +1 more source

Corrigendum to Reduced nicotine in cigarettes in a marketplace with alternative nicotine systems: randomized clinical trial. [PDF]

open access: yesLancet Reg Health Am
Hatsukami DK   +15 more
europepmc   +1 more source

Integrated Metabolic and Inflammatory Clustering Reveals Distinct Risk Profiles for Digestive Diseases

open access: yesAdvanced Science, EarlyView.
This study analyzes 398 432 participants, identifying four distinct metabolic‐inflammatory subtypes. These subtypes show a significant association with digestive disease risk. Cluster‐associated metabolite signatures partially explain this link. Machine learning models using these metabolites accurately predict risk for ten digestive diseases. Key risk
Zhenhe Jin   +10 more
wiley   +1 more source

Miscarriage-Related Acute Kidney Injury: A Case Report

open access: yesInternational Medical Case Reports Journal
Junya Kojima,1 Masanori Ono,1 Koichiro Tasaki,2 Takeshi Nagai,2 Toshitaka Nagao,2 Sho Rinno,3 Yoshihiko Kanno,3 Rie Yoshida,1 Tomoo Suzuki,1 Naoaki Kuji,1 Hirotaka Nishi1 1Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan ...
Kojima J   +10 more
doaj  

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