Results 211 to 220 of about 1,006,914 (379)

Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug‐Resistant Candida albicans

Advanced Science, EarlyView.
To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao, Jiahe Su, Jiawei Yuan, Qinyan Cao, Yue Wu, Yuyang Xiao, Guang Yang, Ruomu Xia, Jingpeng Yang, Yanan Li, Lina Wu, He Huang, Lingtong Meng   +12 more
wiley   +1 more source

Hyperfiltration and Metabolism Before and After a Low-Calorie, Pre-Gastric Bypass Surgery Diet: Significance for Concentrations of Hydrophilic and Lipophilic Drugs. [PDF]

Basic Clin Pharmacol Toxicol
Axelsson MAB, Wallerstedt SM.
europepmc   +1 more source

Serum Creatinine in Pregnancy: A Systematic Review

Kidney International Reports, 2018
K. Wiles, K. Bramham, Paul Townsend Seed, C. Nelson-Piercy, L. Lightstone, L. Chappell   +5 more
semanticscholar   +1 more source

β2‐Microglobulin, Cystatin C, and Creatinine and Risk of Symptomatic Peripheral Artery Disease [PDF]

, 2014
Michel M. Joosten, Jennifer K. Pai, Monica L. Bertoia, Ron T. Gansevoort, Stephan J. L. Bakker, John P. Cooke, Eric B. Rimm, Kenneth J. Mukamal   +7 more
openalex   +1 more source

Gamma Glutamyl Transferase to Creatinine Ratio Measurement [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Synthesis of Bispecific Conjugates by ADP‐Ribosyl Cyclases

Advanced Science, EarlyView.
Genetic fusion of a CD38 enzymatic domain to antibody scaffolds allows site‐specific conjugation of small‐molecule ligands. Using this approach, a PSMA ligand DUPA is conjugated with an anti‐human CD3 Fab antibody. The resulting bispecific anti‐CD3‐DUPA conjugate facilitates recruitment and activation of cytotoxic T cells against PSMA‐expressing ...
Sunny H. Kim, Arshad J. Ansari, Lei Zhang, Guoyun Kao, Thuc Oanh Hoang, Zeyu Zhang, Srinivasarao Singireddi, Benjamin B. Katz, Yong Zhang   +8 more
wiley   +1 more source

Repeat kidney biopsy reveals new-onset IgA nephropathy in a patient with ANCA-associated vasculitis. [PDF]

CEN Case Rep
Iwami S, Eriguchi M, Kosugi T, Furuyama R, Kitamura S, Tanabe K, Matsui M, Samejima KI, Tsuruya K.   +8 more
europepmc   +1 more source

Phenotyping of Acute Kidney Injury: Beyond Serum Creatinine.

Seminars in Nephrology, 2018
D. Moledina, C. Parikh
semanticscholar   +1 more source

Development of a formula for estimated glomerular filtration rate in pregnant women from physiological hyperfiltration of serum creatinine [PDF]

Kwangjin Ahn, Taesic Lee, Jieun Kang, Seong Jin Choi, Sangwon Hwang, Dong Min Seo, Jooyoung Cho, Young Uh   +7 more
openalex   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source