Results 241 to 250 of about 960,906 (340)

A Novel Self‐Regulated, Non‐Directional Magnetic Thermos‐Brachytherapy 125I Seed Enhances Anticancer Efficacy by Rescuing Immune Escape

Advanced Science, EarlyView.
This work constructs magnetic nanoparticles (MNPs) and incorporates them with silver rods coated with 125I to form a novel composite seed, which exhibits direction‐independent and self‐regulated heating efficiency, as well as the capacity of preventing MNPs leakage and enabling repeated hyperthermia.
Bin Xu, Ye‐Ming Wu, Yi‐Fei Cheng, Lei Dong, Shuai‐Wen Ding, Sheng‐Rong Chen, Bin‐Da Chen, Ren‐Peng Yang, Wei‐Hua Zhang, Ya‐Jie Wang, Wei‐Pu Mao, Fan Shi, Zhi‐Cheng Jin, Jian‐Jian Chen, En‐Qi Qiao, Yu‐Qing Wang, Jin‐Ze Li, Peng Zeng, Cheng‐Wei Wu, Wei Zhang, Jin‐Bing Xie, Jian Lu, Gao‐Jun Teng   +22 more
wiley   +1 more source

Cystatin C as a predictor of renal recovery and in hospital mortality in patients with acute kidney injury and liver cirrhosis. [PDF]

BMC Nephrol
Nagy E, Abdelfattah AH, Sayed-Ahmed N, Ahmed S.   +3 more
europepmc   +1 more source

Ultraviolet Absorption Spectra of Creatinine. [PDF]

, 1953
A Wollenberger, Claes Löfman, John C. Olsen, Artturi I. Virtanen, Nils Andreas Sörensen   +4 more
openalex   +1 more source

The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?

Drug Metabolism And Disposition, 2016
X. Chu, K. Bleasby, G. Chan, Irene Nunes, R. Evers   +4 more
semanticscholar   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source

Exploration of mortality-associated creatinine thresholds for acute kidney injury in cardiac surgery patients with impaired kidney function: a single-center retrospective cohort study. [PDF]

BMC Anesthesiol
Jiang W, Xu J, Luo Z, Xu X, Ding X, Fang Y.   +5 more
europepmc   +1 more source

Estimation of blood creatinine [PDF]

, 1942
G. E. Delory, J. Jacklin
openalex   +1 more source

Inhibition of FOXM1 Synergizes with BH3 Mimetics Venetoclax and Sonrotoclax in Killing Multiple Myeloma Cells through Repressing MYC Pathway

Advanced Science, EarlyView.
Relapsed and refractory multiple myeloma remains a major clinical challenge. This study shows that FOXM1 contributes to resistance against BH3 mimetics in multiple myeloma cells. The FOXM1 inhibitor NB73 enhances the effectiveness of BH3 mimetics by reducing FOXM1 expression and suppressing the MYC pathway.
Zhi Wen, Yidan Wang, Kathryn C. Fox, Adam M. Bissonnette, Luke F. Moat, Terrie E. Kitchner, Kelsey Springstroh, Sung Hoon Kim, Dagna S. Sheerar, Patcharon Tanawattanacharoen, Chady A. Leon, Seth O. Fagbemi, John A. Katzenellenbogen, Scott J. Hebbring, Benita S. Katzenellenbogen, Siegfried Janz, Adedayo A. Onitilo   +16 more
wiley   +1 more source

Regulating Enzyme Activity via Microaggregates Mediated by Phase Separation

Advanced Science, EarlyView.
An enzyme‐sequestration strategy for combating postoperative pancreatic fistula (POPF) is developed, employing a D‐peptide called DPMD to induce liquid–solid phase separation (LSPS) of pancreatic proteases. This LSPS‐driven microaggregate approach effectively isolates trypsin and chymotrypsin from their substrates, thereby reducing pancreatic fluid ...
Yang Wang, Juzheng Yuan, Niu Dai, Yanlin Ji, Wenguang Yang, Xiao Li, Siqi Yan, Jin Yan   +7 more
wiley   +1 more source

Evaluation of the Urine Albumin-to-Creatinine Ratio (UAC) for Early Renal Disease: A Large-Scale Clinical Study in Cats. [PDF]

Animals (Basel)
Cha YE, Lee SY, Kang MH, Kang HM, Kang DJ, Park HM.   +5 more
europepmc   +1 more source