Cystatin C as Biomarker for the Evaluation of Renal Outcome in AL Amyloidosis
ABSTRACT Cystatin C (CysC) has emerged as a novel and potentially more reliable biomarker for the estimation of glomerular filtration in the general population in patients with various conditions. In AL amyloidosis, the current renal staging system and renal response criteria are based on proteinuria and creatinine‐based eGFR.
Foteini Theodorakakou+18 more
wiley +1 more source
Association Between Creatinine and Lung Cancer Risk in Men Smokers: A Comparative Analysis with Antioxidant Biomarkers from the KCPS-II Cohort. [PDF]
Shin JW, Nguyen TM, Jee SH.
europepmc +1 more source
Detecting the Difficult: An Intronic NPC1 Variant Hiding in Plain Sight
ABSTRACT An illustration of the importance of manual data review for identifying rare intronic variants adjacent to homopolymers is presented here. A 14‐year‐old male with Niemann‐Pick Type C disease confirmed biochemically was only found to have a heterozygous pathogenic variant by molecular analysis. A manual review of the Next Generation Sequencing (
Caroline Gully Brown+6 more
wiley +1 more source
Challenges in Toxicological Risk Assessment of Environmental Cadmium Exposure. [PDF]
Satarug S.
europepmc +1 more source
Urinary output of creatine and creatinine associated with physical exercise, and its relationship to carbohydrate metabolism [PDF]
W. Hobson
openalex +1 more source
ABSTRACT The MT‐ATP6 gene m.8993T>G pathogenic variant has been associated with Leigh syndrome, especially in patients exhibiting a high degree of heteroplasmy. Although patients may present with a wide phenotypic spectrum, characteristic findings include bilateral, symmetric hyperintensities in the basal ganglia and brainstem on brain MRI ...
Ramya Treitel+2 more
wiley +1 more source
Corrigendum: Frequency, Risk Factors, and Prognosis of Dehydration in Acute Stroke
Elena Cortés-Vicente+6 more
doaj +1 more source
Machine learning based clinical decision tool to predict acute kidney injury and survival in therapeutic hypothermia treated neonates. [PDF]
Keles E+17 more
europepmc +1 more source
MOF Coating Enhances the Ion Tolerance of Micromotors
This work reported a novel method to significantly enhance the ion tolerance of EMNMs using a MOF coating via controllable heteroepitaxial growth, enabling effective motion in high‐salt environments and propulsion through biological tissues under 980 nm NIR light, with potential applications in targeted drug delivery.
Leyan Ou+10 more
wiley +2 more sources
Metabolic alterations in human pulmonary artery smooth muscle cells treated with PDGF‐BB
Metabolic abnormalities are considered to play a key regulatory role in vascular remodeling of pulmonary arterial hypertension. We analyzed the metabolome in the culture supernatants of human pulmonary artery smooth muscle cells (PASMC) during the malignant proliferation phenotype transition via a targeted metabolomics method. Significant and extensive
Meng‐Jie Zhang+9 more
wiley +1 more source