Results 301 to 310 of about 751,137 (338)

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

Annals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek, David F. Hanff, Pim J. French, Sarah A. van Dijk, Erik A.C. Wiemer, Olivier C. Manintveld, Martin J. van den Bent, Walter Taal   +7 more
wiley   +1 more source

Biomarkers of Microcirculatory Dysfunction in Sepsis: A Pilot Prospective Observational Study. [PDF]

Crit Care Explor
Longino A, Martin K, Bourland S, Phinney W, Wood T, Camargo E, Garcia A, Oakes J, Hiller T, Weiss R, Basu A, Douglas I, Hippensteel J.   +12 more
europepmc   +1 more source

Copper‐Containing Mesoporous Bioactive Glass Nanoparticles: A Novel Radiosensitizer for Nonsmall Cell Lung Cancer

Advanced NanoBiomed Research, EarlyView.
Cu‐MBGNs enhance the efficacy of radiotherapy for nonsmall cell lung cancer (NSCLC), exhibiting selective cytotoxicity toward cancer cells while maintaining minimal toxicity to normal cells. Cu‐MBGNs amplify radiation‐induced ROS through silica‐mediated generation and Cu2+/Cu+ redox catalysis.
Jingyi He, Sihong Ouyang, Xiaofeng Chen, Conghua Xie   +3 more
wiley   +1 more source

Sacubitril/valsartan preserves kidney function in rats with cardiorenal syndrome after myocardial infarction. [PDF]

PLoS One
Bergo KK, Nordén ES, Bendiksen BA, Espe EKS, McGinley G, Hauge-Iversen IM, Hussain RI, Leh S, Marti HP, Zhang L, Sjaastad I, Cataliotti A.   +11 more
europepmc   +1 more source

Low‐Dose X‐Ray Radiation Enhances Intratumoral Accumulation and Antitumor Effects of Nanoscale Coordination Polymers via Neutrophil‐Mediated Trafficking

Advanced NanoBiomed Research, EarlyView.
Low‐dose radiotherapy has been shown to direct nanoscale coordination polymers (NCPs) to tumors by promoting neutrophil recruitment. This immune‐mediated delivery strategy markedly enhances tumor targeting and the therapeutic efficacy of NCPs carrying combination chemotherapies or innate immune modulators, even under clinically relevant radiation ...
Langston Tillman, Xiaomin Jiang, Chaoyu Wang, Yuxuan Xiong, Wenbin Lin   +4 more
wiley   +1 more source

Isolated renal sarcoidosis and concurrent secondary membranous nephropathy: a case report. [PDF]

J Med Case Rep
Narayana CA, Safdar F, Harish R, Guo S, Aslam A.   +4 more
europepmc   +1 more source

NEPHROTOXICITY OF CYCLOSPORINE IN LIVER-TRANSPLANTATION [PDF]

, 1984
ESQUIVEL, CO, GORDON, RD, IWATSUKI, S, KLINTMALM, GBG, SHAW, BW, STARZL, TE   +5 more
core  

Case Report: Application of the AngioJet thrombectomy system in acute lower extremity deep vein thrombosis complicated by transplanted renal vein thrombosis (report of two cases). [PDF]

Front Cardiovasc Med
Shao L, Cao G, Shang S, Sun B, Ji W, Zhang J, Liu T.   +6 more
europepmc   +1 more source

Fractional excretion of sodium and 1-year cardiovascular mortality in acute decompensated heart failure, is there any relationship? [PDF]

J Res Med Sci
Sharoubandi SH, Farahani MM, Khosravi A, Rabanipour N.   +3 more
europepmc   +1 more source

Fecal Impaction: An Unusual Cause of Acute Kidney Injury in a Kidney Transplant Recipient. [PDF]

Case Rep Transplant
Tariq H, Ramakrishnan M, Portocarrero P, Gupta M, Herrera N, Klein J, Gupta A, Cibrik D.   +7 more
europepmc   +1 more source