Results 311 to 320 of about 960,906 (340)

Narsoplimab Results in Excellent Survival in Adults and Children With Hematopoietic Cell Transplant Associated Thrombotic Microangiopathy (TA‐TMA)

American Journal of Hematology, EarlyView.
ABSTRACT Inappropriate complement activation is a key driver of hematopoietic cell transplant‐associated thrombotic microangiopathy (TA‐TMA). Treatment with narsoplimab, an inhibitor of MASP‐2, the effector enzyme of the lectin pathway, resulted in a response rate of 61% in a Phase 2 clinical trial in adults with TA‐TMA.
Michelle L. Schoettler, Sunil Kumar Pusarla, Narinder Nangia, Miguel‐Angel Perales, Rafael F. Duarte, Andreas Grauer, Alessandro Rambaldi   +6 more
wiley   +1 more source

Advancing Accuracy in Chronic Kidney Disease Diagnosis and Management: Reference Materials and Reference Measurement Procedures for Clinical Markers. [PDF]

Ann Lab Med
Tan HT, Liu Q, Teo TL.
europepmc   +1 more source

Identification and Characterization of a Novel Biallelic SLC12A2 Variant Associated With Kilquist Syndrome (OMIM #619080)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study presents the case of a child with multiple congenital anomalies, severe hypotonia, and profound bilateral sensorineural hearing loss. Functional bioenergetic assessments showed no significant mitochondrial respiratory defects, and riboflavin (Rf) status evaluation excluded a deficiency in Rf transporters as a cause of hearing loss ...
Piero Leone, Alessia Nisco, Luciana de Gennaro, Maria Tolomeo, Elisa Lorefice, Giuseppe Petrosillo, Silvia Russo, Donatella De Giovanni, Claudia Rita Catacchio, Francesca Romana Lepri, Mario Ventura, Simonetta Simonetti, Albina Tummolo, Maria Barile   +13 more
wiley   +1 more source

Recurrent immunotactoid glomerulopathy in a kidney transplant recipient: Case report. [PDF]

Medicine (Baltimore)
Yu S, Zhao X, Cheng F, Zhao C, Yu J, Wu S, Sun W.   +6 more
europepmc   +1 more source

Psoriasis Does Not Seem to Impair Glomerular and Tubular Function - The Comprehensive Study on Serum and Urine. [PDF]

Psoriasis (Auckl)
Nowowiejska J, Baran A, Hermanowicz JM, Sieklucka B, Koper-Lenkiewicz OM, Kamińska J, Pawlak K, Pawlak D, Flisiak I.   +8 more
europepmc   +1 more source

Dosage Regimen Optimization of Ertapenem Against ESBL-Producing Enterobacterales Infection in Critically Ill Patients Using Monte Carlo Simulation. [PDF]

Clin Transl Sci
Muangkasem A, Nosoongnoen W, Sririttha S, Aramruang T, Montakantikul P.   +4 more
europepmc   +1 more source

Preoperative renal functional reserve as a predictor of acute kidney injury in young adults with congenital heart disease. [PDF]

Sci Rep
Fuhrman DY, Schwartz GJ, Cooper DS, Talisa VB, Hoskoppal AK, Kellum JA.   +5 more
europepmc   +1 more source

Association between the difference in creatinine-based and creatinine-cystatin C-based estimated glomerular filtration rates and vancomycin systemic exposure after ventricular assist device surgery. [PDF]

Transl Clin Pharmacol
Kang J, Song J, Lee S, Yu KS, Huh KY.
europepmc   +1 more source