Results 111 to 120 of about 410,080 (254)

Serum cystatin C: A surrogate marker for the characteristics of peritoneal membrane in dialysis patients

Saudi Journal of Kidney Diseases and Transplantation, 2009
To evaluate whether cystatin C levels can be a surrogate marker of creatinine clearance and reflect the characteristics of peritoneal membrane in dialysis patients, we performed peritoneal equilibration tests (PET) in 18 anuric adult chronic peritoneal ...
Al-Wakeel Jamal, Hammad Durdana, Memon Nawaz, Tarif Nauman, Shah Iqbal, Chaudhary Abdulrauf   +5 more
doaj  

Self‐Amplified Activatable Fluorescent Probe for Early Diagnosis of Acute Kidney Injury and High‐Throughput Screening of Natural Protectants

Advanced Science, EarlyView.
The PS‐QRC nanoprobe employs L‐serine as a targeting ligand for kidney injury molecule‐1 (KIM‐1) to achieve accumulation in injured renal tissues. Upon activation by reactive oxygen species (ROS), it undergoes a self‐amplifying cascade to release fluorophores for near‐infrared fluorescence (NIRF) imaging, enabling ultra‐early diagnosis of acute kidney ...
Yahui Chen, Meihong Liu, Mengchao Ding, Ye Liu, Chuanxu Zhu, Mingye Gong, Zhixuan Huang, Yi Zhang, Wei Xue, Youyong Yuan, Kewei Wang   +10 more
wiley   +1 more source

Creatinine clearance during cimetidine administration for measurement of glomerular filtration rate

, 1992
Creatinine clearance inaccurately estimates true glomerular filtration rate (GFR) because of tubular secretion of creatinine. We studied the ability of oral cimetidine, a blocker of tubular creatinine secretion, to improve the accuracy of measuring ...
de Waart, D. R., van Acker, B. A., Koomen, G. C., Arisz, L., Koopman, M. G.   +4 more
core   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Management of antimicrobial therapy in culture-negative post-neurosurgical meningitis caused by augmented renal clearance

IDCases
Background: Augmented renal clearance (ARC) is a well-recognized driver of subtherapeutic antibiotic concentrations in critically ill patients; however, its occurrence in elective neurosurgical populations remains unrecognized.
Hai Zeng, Xinrong Ou
doaj   +1 more source

History of creatinine clearance: tribute to a forerunner. [PDF]

Clin Kidney J, 2023
Losito A.
europepmc   +1 more source

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

Student´s knowledge about urine collection for creatinine clearance test

, 2020
Clearance kreatininu je jednou ze základních metod využívaných ke stanovení glomerulární filtrace a stanovuje se na podkladě 24hodinového sběru moči.
Svobodová, Lucie
core   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Estimation of Creatinine Clearance in Patients with Cushing's Syndrome

, 1989
The predictive value of the Cockcroft-Gault equation in patients with Cushing's syndrome was evaluated in 23 patients. Patients were subdivided based on total body weight into two groups, obese and nonobese. Estimated creatinine clearance (EC1cr) values
Jimmi Hatton, Robert A. Blouin, Michael D. Parr   +2 more
core   +1 more source