Results 91 to 100 of about 410,080 (254)

Comparison of the Cockcroft-Gault and MDRD equations with the endogenous creatinine clearance to estimate renal function in ambulatory adult patients treated in a peruvian reference hospital

Revista de Nefrología, Diálisis y Trasplante, 2019
Introduction: The estimation of renal function is an important component of hospital care. To do this, estimates are usually used, based on serum creatinine levels. The most widely used equations are MDRD and Cockcroft-Gault.
Alonso Soto, Gladys Patiño Soto
doaj  

Effect of platelet activating factor antagonist treatment on gentamicin nephrotoxicity

Mediators of Inflammation, 1992
To assess whether PAF could be involved in the gentamicin-induced nephrotoxicity, we have studied the effect of PAF antagonist BN-52021 on renal function in rats after gentamicin (GENTA) treatment.
A. Rodriguez-Barbero, E. Bosque, L. Rivas-Cabaero, M. Arévalo, J. M. López-Novoa   +4 more
doaj   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

Frequency of Glomerular Dysfunction in Children with Beta Thalassaemia Major

Sultan Qaboos University Medical Journal, 2014
Objectives: This study investigated the frequency of glomerular dysfunction in children with beta thalassaemia major (β-TM) by using different markers and correlating them with serum ferritin and iron chelation therapy.
Basma A. Ali, Ahmed M. Mahmoud
doaj  

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

The role of a parental history of Balkan endemic nephropathy in the occurrence of BEN: a prospective study

International Journal of Nephrology and Renovascular Disease, 2012
Kesinee Hanjangsit1, Wilfried Karmaus1, Plamen Dimitrov2, Hongmei Zhang1, Jim Burch1, Svetla Tzolova2, Vecihi Batuman3,41Department of Epidemiology and Biostatistics, University of South Carolina, Columbia, SC, USA; 2National Center of Public Health ...
Hanjangsit K, Karmaus W, Dimitrov P, Zhang H, Burch J, Tzolova S, Batuman V   +6 more
doaj  

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Impacto de fatores clínico-laboratoriais selecionados sobre a mortalidade por infarto agudo do miocárdio em pacientes atendidos no Hospital Universitário da Universidade Federal de Santa Catarina num período de dois anos. [PDF]

, 2007
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Berbigier, Eduardo Jardim
core  

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source