Results 71 to 80 of about 410,080 (254)

A Comparative Study of the Creatinine Clearance in 12-hour and 24-hour Timed Urine Collection in Healthy Volunteer

Journal of Nobel Medical College, 2013
Journal of Nobel Medical College Vol.
Raj Kumar Yadav, Binod Yadav, Anitha Devanath   +2 more
doaj   +1 more source

Utility of endogenous creatinine clearance as a measure of renal function in mice [PDF]

, 2004
Utility of endogenous creatinine clearance as a measure of renal function in mice.BackgroundThe use of endogenous plasma creatinine levels and creatinine clearance as a tool to evaluate renal function in mice has come under scrutiny as prior studies have
Breyer, Matthew D., Dunn, Stephen R., Bottinger, Erwin P., Sharma, Kumar, Qi, Zhonghua   +4 more
core   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

Advanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li   +7 more
wiley   +1 more source

Acute peritoneal dialysis adequacy among children at a national referral hospital in Kenya: a cross-sectional study in a resource-limited setting

BMC Nephrology
Background Acute peritoneal dialysis (PD) is an important renal replacement therapy for children with acute kidney injury (AKI), particularly in resource-limited settings.
Doreen Nganga, Bashir Admani, Dalton Wamalwa, Cyriaque Mbarubukeye   +3 more
doaj   +1 more source

Creatinine clearance and risk of early mortality in patients undergoing coronary artery bypass grafting [PDF]

, 2005
ObjectivesWe sought to evaluate renal function assessed on the basis of calculated creatinine clearance as a predictor of early mortality and postoperative complications in patients undergoing coronary artery bypass grafting and to assess whether ...
Klerdal, Kristina, Holzmann, Martin J., Jörgensen, Lena, Ahnve, Staffan, Hammar, Niklas, Pehrsson, Kenneth, Ivert, Torbjörn   +6 more
core   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Methotrexate Associated Renal Impairment Is Related to Delayed Elimination of High-Dose Methotrexate

The Scientific World Journal, 2015
Although Methotrexate (MTX) is an effective drug for the treatment of acute lymphoblastic leukemia (ALL), the toxicity remains a significant problem. In this prospective study, fifty-four patients with ALL were enrolled.
Shi-Long Yang, Fen-Ying Zhao, Hua Song, Di-Ying Shen, Xiao-Jun Xu   +4 more
doaj   +1 more source

Serum cystatin C is not a better marker of creatinine or digoxin clearance than serum creatinine

, 2002
Aims To assess whether cystatin C, a new serum marker of renal function, is a better index of creatinine or digoxin clearance than serum creatinine in older people.
S. O'Riordan, S. Brice, Brice, S, Swift, C G, O'Riordan, S, Ouldred, E, S. H. D. Jackson, E. Ouldred, Jackson, S H D, C. G. Swift   +9 more
core   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Bone disease in patients with chronic kidney disease under conservative management

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Few studies have focused on bone disease in patients with chronic kidney disease under conservative treatment. The objective was to evaluate bone disease in patients with chronic kidney disease.
Carlos Perez Gomes, Maria Inês Barreto Silva, Maria Eugênia Leite Duarte, David Dorigo, Carla Cavalheiro da Silva Lemos, Rachel Bregman   +5 more
doaj   +1 more source