Results 61 to 70 of about 410,080 (254)

Development of urea, creatinine and creatinine clearance as a function of age and sex

open access: yes, 1984
peer reviewedSerum urea and creatinine concentrations were determined in 150 healthy subjects. The formula of Cockcroft and Gault was used in order to calculate creatinine clearance.
Chapelle, Jean-Paul   +5 more
core   +1 more source

52-week efficacy and safety of telbivudine with conditional tenofovir intensification at week 24 in HBeAg-positive chronic Hepatitis B [PDF]

open access: yes, 2013
Background and Aims: The Roadmap concept is a therapeutic framework in chronic hepatitis B for the intensification of nucleoside analogue monotherapy based on early virologic response.
Tawesak Tanwandee (279135)   +50 more
core   +2 more sources

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal   +5 more
wiley   +1 more source

SERUM CYSTATIN C – A NEW MARKER OF GLOMERULAR FILTRATION RATE

open access: yesZdravniški Vestnik, 2004
Background. Estimation of the glomerular filtration rate is an essential part of the evaluation of patients with renal disease. A standard for glomerular filtration rate assessment is CrEDTA clearance. Serum creatinine is the most commonly used marker to
Radovan Hojs   +3 more
doaj  

To Save or not to Save the Kidney: Relieving Unilateral Obstruction May Significantly Improve an Initially Low Split Renal Creatinine Clearance

open access: yesJournal of Urological Surgery, 2016
Objective The aim of this study was to evaluate the change in acute/subacute unilateral renal function after the relief of complete unilateral ureteral obstruction by nephrostomy.
Cenk Murat Yazıcı   +2 more
doaj   +1 more source

Using Estimated Creatinine Clearance for Individualizing Drug Therapy: A Reassessment

open access: yes, 1990
Estimates of renal function are frequently used to design individual dosing regimens. The accuracy of these estimates naturally influences their ability to predict certain pharmacokinetic parameters and appropriate drug dosages.
Curtis L. Smith, Edward M. Hampton
core   +1 more source

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

open access: yesAdvanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan   +9 more
wiley   +1 more source

(The) Study of Creatinine Clearance in Neonates

open access: yes, 1986
The creatinine clearance rate, an index of glomerulr filtration, has been reported to develop according to getational and postnatal age. The purpose of this study is to examine changes clearance with gestational age and postnatal age in preterm and full
홍동선
core   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

Short Term Effects of Diltiazem on Renal Functions: A Controlled Clinical Study

open access: yesTurkish Journal of Nephrology, 2019
OBJECTIVE: We aimed to study acute effects of diltiazem on renal functions and its renoprotective effects in patients with chronic kidney disease (CKD).
Savaş ÖZTÜRK   +7 more
doaj  

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