Results 41 to 50 of about 410,080 (254)

Plasma proenkephalin‐a facilitates measurement of human kidney functional reserve: From healthy kidney donors to polymorbid patients

Physiological Reports
Reduced kidney functional reserve, KFR, predicts poor outcomes in kidney diseases. We compared plasma proenkephalin‐A, plasma cystatin C, and creatinine clearance for kidney functional reserve measurement.
Camila Eleuterio Rodrigues, Amy Y. M. Au, Daniel Rebello, Maria Maawad, Florian Uhle, Jonathan Erlich, Zoltan H. Endre   +6 more
doaj   +1 more source

Case Report: Subtherapeutic Vancomycin and Meropenem Concentrations due to Augmented Renal Clearance in a Patient With Intracranial Infection Caused by Streptococcus intermedius

Frontiers in Pharmacology, 2021
Streptococcus intermedius occasionally causes brain abscesses that can be life-threatening, requiring prompt antibiotic and neurosurgical treatment. The source is often dental, and it may spread to the eye or the brain parenchyma. We report the case of a
Marcus Fransson, Anders Helldén, Åse Östholm Balkhed, Dženeta Nezirević Dernroth, Maria Ha, Mats Haglund, Peter Milos, Håkan Hanberger, Bertil Kågedal   +8 more
doaj   +1 more source

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

Advanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng, TzuChun Chung, Katpady Akhil Tantry, Siyu Wu, Jing Tian, Yunqi Cui, Lanyu Li, Yongzan Zhou, Zhilei Zhang, Zhe Su, Gaili Cao, Kun‐Wei Yeh, Ruipeng Li, Xianghui Xiao, Adam F. G. Leontowich, Yuan‐Yu Hsueh, Zhao Pan, Kam C. Tam, Badri Narayanan, Song Li, Yimin. A. Wu   +20 more
wiley   +1 more source

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

Selective Laser Sintering and Graphitization for Mono‐Matrix Unibody Fabrication of Integrated Stereo‐Circuit and Stereo‐Fluidic Wearable Electronics

Advanced Materials, EarlyView.
A novel selective laser sintering and graphitization (SLSG) 3D printing technology enables unibody fabrication of compacted insulating structures and conductive circuits in fluidic‐integrated wearable electronics through adaptive photonic modulation.
Li Zhang, Wing Cheung Mak
wiley   +1 more source

Antiretroviral therapy dose adjustments based on calculated creatinine clearance [PDF]

, 2009
Background: Whereas therapy for HIV is dependent on level of creatinine clearance, most laboratories locally only report an absolute creatinine value. There is likelihood that the patients already on antiretroviral therapy (ART) may have required dosage ...
G Tesfaldet, Shavadia, J., Twahir, Majid, M Twahir, Twahir, M, Shavadia, J, Tesfaldet, G, Tesfaldet, G., J Shavadia   +8 more
core   +1 more source

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

Advanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng, Qinghuan Shen, Junqi Zhang, Jiawen Liu, Zeping Gui, Zijie Wang, Qianguang Han, Shuang Fei, Hao Chen, Li Sun, Jun Tao, Zhijian Han, Xiaobing Ju, Min Gu, Jianjian Zhang, Ruoyun Tan   +15 more
wiley   +1 more source

Correlation of Beta-2 Microglobulin with serum creatinine and creatinine clearance in patients with different levels of renal function

Gomal Journal of Medical Sciences, 2012
Background: Chronic kidney disease is a major health problem in Pakistan. Serum creatinine is the most common test used to assess renal function. This study was aimed to evaluate the levels of β2 Microglobulin and creatinine in individuals with different
Shahjahan, Riffat Yasmin, Muhammad Amin Jan Mahsud, Mahnoor Khan, Jawaid Subzwari, Javaid Hussain   +5 more
doaj  

Increased Glomerular Filtration Rate in Early Stage of Balkan Endemic Nephropathy

Medicina, 2019
Background: A previous study indicated that Balkan endemic nephropathy (BEN) patients in the early stage of the disease had significantly higher creatinine clearance (Ccr) than healthy persons.
Ljubica Djukanović, Višnja Ležaić, Danica Bukvić, Dušan Mirković, Ivko Marić   +4 more
doaj   +1 more source

Ratio of creatinine clearance (CrCl) in minocycline vs. placebo group, adjusted for baseline creatinine clearance.^*

, 2016
Ratio of creatinine clearance (CrCl) in minocycline vs. placebo group, adjusted for baseline creatinine clearance.*
Sharon G. Adler (498428), Lili Tong (1781044), Anuja P. Shah (2577499), Jenny I. Shen (2577496), Youngju Pak (2577490), Ying Wang (11406), Ali Andalibi (56401), Janine A. LaPage (2577493)   +7 more
core   +1 more source