Results 51 to 60 of about 387,760 (267)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Accumulation of Hydrogen Cyanide Contributes to Bitterness in Bulbs

open access: yesNatural Product Communications
Objective/Background Lilium species possess notable medicinal properties, but their use is often limited by a bitter taste that reduces consumer acceptance. The molecular mechanisms underlying this bitterness remain unclear.
Xianhui Huang   +11 more
doaj   +1 more source

Characterization of Two Gonadal Genes, zar1 and wt1b, in Hermaphroditic Fish Asian Seabass (Lates calcarifer)

open access: yesAnimals
Zygote arrest-1 (Zar1) and Wilms’ tumor 1 (Wt1) play an important role in oogenesis, with the latter also involved in testicular development and gender differentiation.
Han Cui   +8 more
doaj   +1 more source

Creation and Science in the Middle Ages

open access: yesNew Blackfriars, 2007
AbstractThe reception of Greek learning in mediaeval Islam, Judaism, and Christianity was the occasion for a profound analysis of many theological doctrines. In particular, Neoplatonism and Aristotelian philosophy led to renewed thinking about what it means for God to be the Creator of all that is.
openaire   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Enhanced Regional Electric Potential Difference of Graphdiyne Through Asymmetric Substitution Strategy Boosts Li+ Migration in Composite Polymer Solid-State Electrolyte

open access: yesNano-Micro Letters
Highlights Methoxy-substituted graphdiyne (OGDY) is synthesized via an asymmetric substitution strategy, featuring a periodic alternation of electron-rich regions and electron-deficient regions, which significantly enhances the heterogeneity of charge ...
Chao Jiang   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

CRISPR/Cas9-Mediated Knockout of BmGDAP2 in the Silkworm, Bombyx mori: Extended Lifespan and Altered Gene Expression Impacting Developmental Pathways

open access: yesInsects
Ganglioside-induced differentiation-associated protein 2 (GDAP2) is a gene involved in hereditary cerebellar ataxia. At present, little is known about the function of GDAP2 in insects.
Chaojun Yuan   +12 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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